Caffeic acid (#CFN99190), luteolin (#CFN98784), luteolin 7-O-glucoside (#CFN98565), cosmosiin (#CFN98981), homoplantaginin (#CFN90344), apigenin (#CFN98843), and hispidulin (#CFN99491) were purchased from ChemFaces (Wuhan, China). PD-1/PD-L1 inhibitor screening assay kit (#72005), CTLA-4 (cytotoxic T-lymphocyte-associated protein 4)/CD80 inhibitor screening assay kit (#72009), and PD-L1-blocking antibody (#71213) were purchased from BPS Bioscience (San Diego, CA, USA). Small molecule PD-L1 inhibitor C1 (BMS-1, # T3655) was purchased from TargetMol (Wellesley Hills, MA, USA). Anti-PD-1 antibody (Pembrolizumab, #A2005) and anti-CTLA-4 antibody (#A2001) was purchased from Selleck Chemicals (Houston, TX, USA).
Anti pd 1 antibody pembrolizumab
Manufactured by Selleck Chemicals
Sourced in United States
Anti-PD-1 antibody (Pembrolizumab) is a monoclonal antibody that binds to the programmed cell death-1 (PD-1) receptor. It is used in research applications to study immune checkpoint inhibition.
Automatically generated - may contain errors
Lab products found in correlation
Cosmosiin, by ChemFaces (1 mentions)
Luteolin 7 o glucoside, by ChemFaces (1 mentions)
Pd 1 pd l1 inhibitor screening assay kit, by BPS Biosciences (1 mentions)
Anti ctla 4 antibody, by Selleck Chemicals (1 mentions)
Hispidulin, by ChemFaces (1 mentions)
Caffeic acid, by ChemFaces (1 mentions)
Ctla 4, by BPS Biosciences (1 mentions)
Apigenin, by ChemFaces (1 mentions)
Luteolin, by ChemFaces (1 mentions)
Asparaginase, by Merck Group (1 mentions)
Glutamine, by Merck Group (1 mentions)
13c glutamine, by Merck Group (1 mentions)
Nk 92, by American Type Culture Collection (1 mentions)
2 protocols using anti pd 1 antibody pembrolizumab
1
Immune Checkpoint Inhibitor Screening Assays
2
Culturing and Characterizing NK Cell Lines
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Natural-killer cell line NK-92 (Cat# CRL-2407) was available from American Type Culture Collection (Manassas, VA, USA). SNK-6 was kindly provided by Professor Norio Shimizu and Yu Zhang of Chiba University. Cell lines were authenticated using Short Tandem Repeat (STR) analysis (Genetic Testing Biotechnology, STR Profile Reports in Supplemental Data). Recent mycoplasma testing has been performed with Lonza LT07-705 MycoAlert™ PLUS Mycoplasma Detection Kit. NK-92 cells were cultured in α-MEM medium supplemented with 10% FBS, 10% HBS and recombinant human IL-2 (20ng/ml). SNK-6 cells were cultured in RPMI-1640 medium supplemented with 10% FBS, 10% HBS and recombinant human IL-2 (80ng/ml). Asparaginase (Cat# A3809), 13C-glutamine (Cat# 184161-19-1), and glutamine (Cat# 56-85-9) were obtained from Sigma-Aldrich (St.Louis, MO, USA). Anti-PD-1 antibody pembrolizumab (Cat# A2005) was from Selleck Chemicals (Houston, TX, USA).
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