N n dicyclohexyl carbonate diimide

Manufactured by Maclin Biochemical Technology

Sourced in China

N,N‐dicyclohexyl carbonate diimide is a reagent commonly used in organic synthesis for the activation of carboxyl groups. It is a coupling agent that facilitates the formation of amide bonds between carboxylic acids and amines.

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Lab products found in correlation

1 3 5 trimethylbenzene, by Maclin Biochemical Technology (2 mentions) Aminopropyltriethoxysilane aptes, by Energy Chemical (2 mentions) 1 3 dimethylaminopropyl 3 ethylcarbodiimide hydro edc, by Maclin Biochemical Technology (2 mentions) N hydroxysuccinimide, by Maclin Biochemical Technology (2 mentions) Hexadecyl trimethyl ammonium bromide ctab, by Tianjin Kemiou Chemical Reagent (2 mentions) 4 dimethylaminopyridine, by Maclin Biochemical Technology (1 mentions) Tetraethyl orthosilicate teos, by Sinopharm (1 mentions) Anhydrous tetrahydrofuran thf, by Sinopharm (1 mentions) 4 dimethylaminopyridine dmap, by Maclin Biochemical Technology (1 mentions) Tetraethyl orthosilicate, by Sinopharm (1 mentions)

2 protocols using n n dicyclohexyl carbonate diimide

Silane-Functionalized Nanoparticle Synthesis

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NH₃·H₂O (AR, 25–28%) was purchased from Xi'an Sanpu Chemical Reagent Co., Ltd. (Xi'an, China). Aminopropyltriethoxysilane (APTES) was purchased from Energy Chemical (Shanghai, China). Ethylenebis(oxyethylenenitrilo)tetraacetic acid (EGTA), trimethyl[3‐(trimethoxysilyl)propyl]ammonium chloride (≈50% methanol), TPP, N,N‐dicyclohexyl carbonate diimide (DCC), 4‐dimethylaminopyridine (DMAP), 1‐(3‐dimethylaminopropyl)‐3‐ethylcarbodiimide hydro (EDC), N‐hydroxysuccinimide (NHS), and 1,3,5‐trimethylbenzene (TMB) were obtained from Shanghai Macklin Biochemical Co. Tetraethylorthosilicate (TEOS, 99.0%) was purchased from Sinopharm Chemical Reagent Co., Ltd. (Xi'an, China). Hexadecyl trimethyl ammonium bromide (CTAB) was purchased from Tianjin Kemiou Chemical Reagent Co., Ltd. (Tianjin, China). Dimethyl sulfoxide (DMSO), toluene, hydrochloric acid, and sodium hydroxide were purchased from Tianjin HengXing Chemical Reagent Co., Ltd. (Tianjin, China).

Zhai Q., Chen X., Fei D., Guo X., He X., Zhao W., Shi S., Gooding J.J., Jin F., Jin Y, & Li B. (2021). Nanorepairers Rescue Inflammation‐Induced Mitochondrial Dysfunction in Mesenchymal Stem Cells. Advanced Science, 9(4), 2103839.

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Synthesis of Amino-Functionalized Silica Nanoparticles

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NH₃·H₂O (AR, 25–28%) was purchased from Xi’an Sanpu Chemical Reagent Co., Ltd. (Xi’an, China). Aminopropyltriethoxysilane (APTES) was purchased from Energy Chemical (Shanghai, China). EGTA, trimethyl [3-(trimethoxysilyl) propyl] ammonium chloride (TMA) (≈50% methanol), TPP, N,N-dicyclohexyl carbonate diimide (DCC), 4-dimethylaminopyridine (DMAP), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydro (EDC), N-hydroxysuccinimide (NHS), and 1,3,5-trimethylbenzene (TMB) were obtained from Shanghai Macklin Biochemical Co. Tetraethylorthosilicate (TEOS, 99.0%), anhydrous tetrahydrofuran (THF) was purchased from Sinopharm Chemical Reagent Co., Ltd. (Xi’an, China). Hexadecyl trimethyl ammonium bromide (CTAB) and PEG (4000) was purchased from Tianjin Kemiou Chemical Reagent Co., Ltd. (Tianjin, China). Dimethyl sulfoxide (DMSO), toluene, hydrochloric acid, and sodium hydroxide were purchased from Tianjin HengXing Chemical Reagent Co., Ltd. (Tianjin, China). 3-bromopropionic acid was purchased from Shanghai Aladdin Bio-Chem Technology Co., LTD (Shanghai, China).

Lei X., Tan G., Wang Y., Chen L., Cao Y., Si B., Zhen Z., Li B., Jin Y., Wang W, & Jin F. (2023). Mitochondrial Calcium Nanoregulators Reverse the Macrophage Proinflammatory Phenotype Through Restoring Mitochondrial Calcium Homeostasis for the Treatment of Osteoarthritis. International Journal of Nanomedicine, 18, 1469-1489.

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