Signa hdx 0m5 twinspeed scanner

MRI scans were obtained with a 1.5 Tesla GE Signa HDx 0M5 TwinSpeed scanner (GE Healthcare, Wukesha, WI) (TE = 3.0 msec, TR = 8.7 msec, TI = 270 msec, flip angle = 8°, delay = 750 msec, bandwidth = ± 15.63 kHz, field of view = 24 cm, matrix = 192 × 192, voxel size = 1.25 × 1.25 × 1.2 mm). Real-time, prospective motion tracking and correction (PROMO) was used to correct for motion artifacts (Brown et al., 2010 (link)). Extensive information regarding the spiral navigator pulse sequences and an extended Kalman filter algorithm used is found in White et al. (2010) (link). AtlasTrack automated DTI was used to produce the white matter streamlines (Hagler et al., 2009 (link)). Of note, UF in the current study involves the bundle of fibers connecting the orbitofrontal region to the anterior temporal lobe, inclusive of the amygdala.

A 1.5 Tesla GE Signa HDx 0M5 TwinSpeed scanner (GE Healthcare, Wukesha, WI) was employed to acquire the high resolution T1-weighted MRI scans (echo time = 3.0 msec, repetition time = 8.7 msec, inversion time = 270 msec, flip angle = 8°, delay time = 750 msec, bandwidth = ± 15.63 kHz, field of view = 24 cm, matrix = 192 × 192, voxel size = 1.25 × 1.25 × 1.2 mm). Given individuals with WS endorse significant fears and anxieties (Dykens, 2003 (link)), additional measures were applied to ensure the utility and reliability of the images obtained. Real-time, prospective motion tracking and correction (PROMO) was applied with spiral navigator pulse sequences and an extended Kalman filter algorithm (Roddey et al., 2003; Shankaranarayanan et al., 2007 ; White et al., 2010 (link)), as an effort to correct artifacts produced by head motion, and improve reliability of morphological indices (Brown et al., 2010 (link); Kuperman et al., 2011 (link)). Application of PROMO improves the diagnostic utility of the MRI data obtained particularly in clinical populations and younger age groups that struggle with the situational contexts and demands of scanning procedures (Brown et al., 2010 (link); Kuperman et al., 2011 (link)).

A 1.5 Tesla GE Signa HDx 0M5 TwinSpeed scanner was used to obtain MRI scans (GE Healthcare, Wukesha, WI) (TE = 3.0 msec, TR = 8.7 msec, TI = 270 msec, flip angle = 8°, delay = 750 msec, bandwidth = ± 15.63 kHz, field of view = 24 cm, matrix = 192 × 192, voxel size = 1.25 × 1.25 × 1.2 mm). Real-time, prospective motion tracking and correction (PROMO) was employed to correct for motion artifacts (Brown et al., 2010 (link)). Information regarding the spiral navigator pulse sequences and an extended Kalman filter algorithm applied in this study is found in White et al., (2010) (link). AtlasTrack automated DTI was used to produce the white matter streamlines (see Hagler et al., 2009 (link)). The methods implemented to process the MRI data are described in detail in Brown et al. (2012) (link), and Mills et al. (2013a (link); 2013b (link)).