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Organic solvents and reagents

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Thermo Fisher Scientific's organic solvents and reagents are high-quality laboratory chemicals used for a variety of applications in scientific research and analysis. They provide the necessary solvents and reagents for reactions, extractions, and other laboratory processes. The products are available in various grades and packaging options to meet the specific needs of our customers.

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Lab products found in correlation

Wang resin, by AnaSpec (5 mentions) Fmoc protected amino acids, by AnaSpec (5 mentions) Trypsin, by Merck Group (1 mentions) α chymotrypsin, by Merck Group (1 mentions)

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Organic solvents (24 citations) Solvents and reagents (2 citations)

5 protocols using organic solvents and reagents

1

Organic Synthesis Reagents Protocol

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Organic solvents and reagents were purchased from Fisher Scientific, Sigma-Aldrich, or Acros Organics and used without further purification. FMOC-protected amino acids and Wang resins were purchased from Anaspec, Inc or Chem-Impex International. PIMT was purchased from Fitzgerald Industries (Cat. # 80R-1342), SAM was purchased from Sigma (a7007), and tris base from Fisher Bioreagents (BP152).
Silzel J.W., Lambeth T.R, & Julian R.R. (2022). PIMT-Mediated Labeling of L-isoAspartic Acid with Tris Facilitates Identification of Isomerization Sites in Long-Lived Proteins. Journal of the American Society for Mass Spectrometry, 33(3), 548-556.
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2

Peptide Synthesis and Purification

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Organic solvents and reagents were purchased from Fisher Scientific, Sigma-Aldrich, or Acros Organics and used without further purification. FMOC-protected amino acids and Wang resins were purchased from Anaspec, Inc or Chem-Impex International. Trypsin was purchased from Sigma Aldrich (T0303). α-chymoTrypsin was also purchased from Sigma Aldrich (C-4129).
Silzel J.W., Ben-Nissan G., Tang J., Sharon M, & Julian R.R. (2022). The Influence of Asp Isomerization on Trypsin and Trypsin-like Proteolysis. Analytical chemistry, 94(44), 15288-15296.
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3

Organic Solvent-based Amino Acid Synthesis

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Organic solvents and reagents were purchased
from Fisher Scientific and Sigma-Aldrich and were used without further
purification. Fmoc-protected amino acids and Wang resins were purchased
from Anaspec Inc. or Chem-Impex International.
Wu H.T., Van Orman B.L, & Julian R.R. (2024). Localizing Isomerized Residue Sites in Peptides with Tandem Mass Spectrometry. Journal of the American Society for Mass Spectrometry, 35(4), 705-713.
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4

Peptide Synthesis Using Commercial Reagents

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Organic solvents and reagents were purchased from Fisher Scientific, Sigma-Aldrich, or Acros Organics and used without further purification. FMOC-protected amino acids and Wang resins were purchased from Anaspec, Inc or Chem-Impex International. Glu isomers were purchased from CarboSynth.
Riggs D.L., Silzel J.W., Lyon Y.A., Kang A.S, & Julian R.R. (2019). Analysis of Glutamine Deamidation: Products, Pathways, and Kinetics. Analytical chemistry, 91(20), 13032-13038.
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5

Organic Solvent Purification and Reagent Use

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Organic
solvents and reagents were purchased
from Fisher Scientific and Sigma-Aldrich and were used without further
purification. FMOC-protected amino acids and Wang resins were purchased
from Anaspec, Inc. or Chem-Impex International.
Wu H.T., Riggs D.L., Lyon Y.A, & Julian R.R. (2023). Statistical Framework for Identifying Differences in Similar Mass Spectra: Expanding Possibilities for Isomer Identification. Analytical Chemistry, 95(17), 6996-7005.
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