Nova head coil

Diffusion MRI and structural T1‐weighted sagittal 3D SPGR MRI data were acquired at Macquarie Medical Imaging at Macquarie University Hospital (Sydney, Australia) as previously described (Grieve et al., 2013). Acquisition was performed using a 3‐Tesla GE Discovery MR750w MRI scanner (General Electric Healthcare, Milwaukee, Wisconsin) running DV25.1 software and using a 32‐channel Nova head coil. A contiguous AC‐PC aligned sagittal MPRAGE PROMO T1‐weighted image was acquired using the following parameters: TR = 8.39 ms, TE = 3.17 ms, TI = 900 ms, flip angle = 8°, matrix = 256 × 256, 198 slices, and 1 mm isotropic voxels. A multi‐shell multi‐band (factor = 3) diffusion pulse sequence was used for dMRI with a phase offset applied to each multi‐band component. We also acquired a b = 0 volume with reversed phase‐encoding for distortion and eddy‐current correction. Each dMRI dataset comprised 140 volumes of unique gradient directions (25 volumes at b = 700 s/mm², 40 volumes at b = 1000 s/mm², 75 volumes at b = 2,800 s/mm²) and eight interleaved b = 0 volumes, acquired with TR = 3,245 ms, TE = 100 ms, flip angle = 90°, 128 × 128 acquisition matrix, 66 slices, 2 mm isotropic voxels and FOV = 240 mm.