Mouse anti mek1 2

Manufactured by Abcam

Mouse anti-MEK1/2 is a primary antibody that specifically recognizes the extracellular signal-regulated kinase kinase 1 and 2 (MEK1 and MEK2) proteins. MEK1 and MEK2 are key components of the mitogen-activated protein kinase (MAPK) signaling pathway, which plays a crucial role in cellular processes such as proliferation, differentiation, and survival.

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MEK1/2 (10 citations) Anti-MEK1/2 (9 citations) Mouse anti (2 citations)

1 protocol using mouse anti mek1 2

Protein Expression Profiling in ATII Cells after MC-LR Exposure

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Proteins were purified from lungs or ATII cells after exposure to MC-LR for 48 h. Western blot analysis of cellular lysates was performed as previously described (Wang et al., 2014 (link)). The following primary antibodies were employed: Rabbit anti-CK18, rabbit anti-CK19, rabbit anti-SP-C, rabbit anti-E-cadherin, rabbit anti-ZO-1, rabbit anti-occludin, rabbit anti-vimentin, rabbit anti-ERK1/2, rabbit anti-p-ERK1/2, rabbit anti-Akt, rabbit anti-p-Akt, mouse anti-MEK1/2, rabbit anti-p-MEK1/2, rabbit anti-PTEN, rabbit anti-GAPDH, mouse anti-MEK1/2 and mouse anti-β-actin (Abcam Inc. Cambridge, MA). Horseradish peroxidase-conjugated goat anti-rabbit/mouse IgG (Boster, Wuhan, China) was used as the secondary antibody. Immunoreactive protein bands were detected using an Odyssey Scanning System (LI-COR Inc).

Wang C., Gu S., Yin X., Yuan M., Xiang Z., Li Z., Cao H., Meng X., Hu K, & Han X. (2016). The toxic effects of microcystin-LR on mouse lungs and alveolar type II epithelial cells. Toxicon : official journal of the International Society on Toxinology, 115, 81-88.

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