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Surveyor pda detector

Manufactured by Thermo Fisher Scientific
Sourced in Switzerland

The Surveyor PDA detector is a high-performance photodiode array (PDA) detector designed for liquid chromatography (LC) applications. It provides sensitive and accurate detection of a wide range of compounds. The Surveyor PDA detector can monitor multiple wavelengths simultaneously, enabling efficient separation and identification of complex sample components.

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2 protocols using surveyor pda detector

1

LCMS Analysis of Chemical Compounds

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LCMS
was performed using a system consisting of the following components:
Shimadzu SCL-10A VP system controller with Shimadzu LC-10 AD VP liquid
chromatography pumps with an Alltima C18 3 u (50 × 2.1 mm) reversed-phase
column and gradients of water–acetonitrile supplemented with
0.1% formic acid, a Shimadzu DGU 20A3 prominence degasser, a Thermo
Finnigan surveyor auto sampler, a Thermo Finnigan surveyor PDA detector,
and a Thermo Scientific LCQ Fleet. Gradients were run from 5% MeCN
to 100% MeCN over a 15 min period.
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2

HPLC-PDA-MS Quantification of Drugs

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The high-performance liquid chromatography (HPLC)-photodiode array (PDA)-MS system consisted of a surveyor MS HPLC pump (Thermo Fisher Scientific Inc, Waltham, Massachusetts), HTC PAL autosampler with cooled stack (CTC Analytics AG, Zwingen, Switzerland) and a surveyor PDA detector (Thermo Fisher Scientific Inc) equipped with a linear trap quadrupole linear ion-trap LC-MS (Thermo Fisher Scientific Inc). Chromatographic separations were achieved by gradient elution using a Waters symmetry C 18 (2.1 mm  50 mm, 3.5 mm particle size) column which was operated at room temperature. Data were acquired and interpreted with Xcalibur software version 2.0 (Thermo Fisher Scientific Inc). For the in vitro experiments, the concentrations of the test compounds CPX, CPZ, DIC, LVX, 8-MOP, and TIM were measured using HPLC. Standard calibration curves of the test compounds were always included during measurements. More details about the analytical conditions that were applied and the calibration range of the analytical methods can be found in supporting information.
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