Arsenic trioxide

Manufactured by Yuanye Bio-Technology

Sourced in China

Arsenic trioxide is a laboratory chemical compound with the chemical formula As2O3. It is a white or colorless, odorless, crystalline solid that is soluble in water. Arsenic trioxide serves as a source of arsenic in various chemical reactions and analytical procedures.

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Lab products found in correlation

Crocetin, by Yuanye Bio-Technology (1 mentions) β actin, by Zhongshan Jinqiao Biotechnology (1 mentions)

2 protocols using arsenic trioxide

Arsenic Trioxide and Baicalin Protocol

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Arsenic trioxide was supplied by Shanghai Yuanye Biotechnology Co., Ltd. in China. Baicalin (purity >95%) was offered by Aladdin Biochemical Technology Co., Ltd. in China. Kits for detecting liver function markers and oxidative stress factors were purchased from the Nanjing Jiancheng Bioengineering Institute in China. The reagent for detecting As deposition was provided by Hebei Bio-high Technology Development CO., Ltd. in China. Unless otherwise specified, all other chemical reagents were analytical grade and furnished by Wuhan Servicebio Technology CO., Ltd. in China.

He Q., Sun X., Zhang M., Chu L., Zhao Y., Wu Y., Zhang J., Han X., Guan S, & Ding C. (2022). Protective effect of baicalin against arsenic trioxide-induced acute hepatic injury in mice through JAK2/STAT3 signaling pathway. International Journal of Immunopathology and Pharmacology, 36, 20587384211073397.

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Crocetin and ATO Antioxidant Mechanism

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Crocetin with HPLC purity of ≥ 98% and arsenic trioxide (ATO, MW:197.84) were procured from Shanghai Yuanye Biotechnology Co., Ltd. (Shanghai, China). Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), malondialdehyde (MDA), glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD) detection kits were procured from Jiancheng Bioengineering Institute of Nanjing (Nanjing, Jiangsu, China). The ROS detection kit was procured from Wuhan Servicebio Technology, Co., Ltd (Wuhan, China). Antibodies specific for Nrf2 and NQO1 were procured from Bioworld Technology, Co., Ltd. (Nanjing, Jiangsu, China). HO-1 antibodies were obtained from Wuhan Sanying Biotechnology Co., Ltd (Wuhan, China). β-actin was procured from Beijing Zhongshan Jinqiao Biotechnology Co., Ltd (Beijing, China). The IL-6, IL-1β, and TNF-α enzyme-linked immunosorbent assay (ELISA) kits were obtained from Wuhan Servicebio Technology CO., Ltd (Wuhan, China).

Liu Y., Liang Y., Zheng B., Chu L., Ma D., Wang H., Chu X, & Zhang J. (2020). Protective Effects of Crocetin on Arsenic Trioxide-Induced Hepatic Injury: Involvement of Suppression in Oxidative Stress and Inflammation Through Activation of Nrf2 Signaling Pathway in Rats. Drug Design, Development and Therapy, 14, 1921-1931.

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