PIM447 (17 (link)) was provided by Novartis Oncology. Buparlisib (BKM120) (18 (link)), AZD1208 (19 (link)), AZD5363 (20 (link)), and Torin1 (21 (link)) were purchased from AdooQ Bioscience. CM-H2DCF-DA (22 (link)) was from Molecular Probes (Thermo Scientific). All other chemicals were purchased from Sigma-Aldrich.
Pim447
Manufactured by Novartis
Sourced in Switzerland
PIM447 is a laboratory equipment product developed by Novartis. It is designed to perform a specific function, but a detailed description cannot be provided while maintaining an unbiased and purely factual approach. Additional information about the intended use or interpretation of the product's capabilities is not available.
Automatically generated - may contain errors
Lab products found in correlation
Azd1208, by Adooq (2 mentions)
Cm h2dcfda, by Thermo Fisher Scientific (1 mentions)
Torin 1, by Adooq (1 mentions)
Azd5363, by Adooq (1 mentions)
Azd1208, by Selleck Chemicals (1 mentions)
Aeb071, by Novartis (1 mentions)
Hrp linked mouse igg, by GE Healthcare (1 mentions)
Anti ha, by Cell Signaling Technology (1 mentions)
Anti pim2, by Cell Signaling Technology (1 mentions)
Anti pim3, by Cell Signaling Technology (1 mentions)
Anti pim1, by Cell Signaling Technology (1 mentions)
Hrp conjugated anti β actin, by Merck Group (1 mentions)
3 protocols using pim447
1
Cell Signaling Pathway Inhibition Assay
2
Investigating Targeted Cancer Therapies
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3
Probing Protein Kinase Signaling in Stem Cells
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Primary antibodies used for western blotting included anti‐PIM1 (Cell Signaling Technology, Cat # 2907), anti‐PIM2 (Cell Signaling Technology, Cat # 4730), anti‐PIM3 (Cell Signaling Technology, Cat # 4165), anti‐pIRS1‐S1101 (Cell Signaling Technology, Cat # S1101 Cat # 2385), anti‐insulin receptor substrate 1 (IRS1; Cell Signaling Technology, Cat # 06‐248), anti‐HA (Cell Signaling Technology, Cat # 14031), anti‐SOX2 [(E‐4) sc‐365823; Santa Cruz Biotech, Santa Cruz, CA, USA], anti‐OCT‐4 [(C‐10) sc‐5279; Santa Cruz Biotech], and anti‐NANOG [(5A10) sc‐134218; Santa Cruz Biotech]. HRP‐conjugated anti‐β‐actin (Cat # A3854) was purchased from Sigma‐Aldrich. HRP‐linked mouse IgG (Cat # NA931V) and rabbit IgG (Cat # NAV934V) were purchased from GE Healthcare Life Sciences (Princeton, NJ, USA).
Doxycycline (Dox) hydrochloride (Cat # D3447) was purchased from Sigma‐Aldrich. AZD1208 (Cat # A13203) was purchased from Adooq Bioscience (Irvine, CA, USA). Enza (MDV3100; Cat # S1250) was purchased from Selleckchem (Houston, TX, USA). PIM447 was a gift from Novartis (Basel, Switzerland).
Doxycycline (Dox) hydrochloride (Cat # D3447) was purchased from Sigma‐Aldrich. AZD1208 (Cat # A13203) was purchased from Adooq Bioscience (Irvine, CA, USA). Enza (MDV3100; Cat # S1250) was purchased from Selleckchem (Houston, TX, USA). PIM447 was a gift from Novartis (Basel, Switzerland).
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