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Akt1 2 sirna

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AKT1/2 siRNA is a small interfering RNA (siRNA) that targets the AKT1 and AKT2 genes. It is designed to modulate the expression of these genes, which play a role in various cellular processes.

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Lab products found in correlation

Sigenome sirnas for the human hif1α, by Horizon Discovery (2 mentions) Dharmafect 1, by Horizon Discovery (2 mentions)

Spelling variants of this product

Akt1/2 (10 citations) SiRNAs (4 citations) Akt1 siRNA (2 citations) SiRNA II (2 citations)

2 protocols using akt1 2 sirna

1

Knockdown of HIF1α and AKT1/2 in NSCLC

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The siGENOME siRNAs for the human HIF1α were obtained from Dharmacon (Lafayette, CO). AKT1/2 siRNA were purchased from Cell Signaling. H2228 or H3122 were transfected with siRNAs using DharmaFECT 1 according to the manufacturer (Dharmacon). Twenty-four hours after transfection, cells were incubated with fresh complete medium for another 48 hours before protein and mRNA analysis.
Ma Y., Yu C., Mohamed E.M., Shao H., Wang L., Sundaresan G., Zweit J., Idowu M, & Fang X. (2016). A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer. Oncogene, 35(47), 6132-6142.
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2

Knockdown of HIF1α and AKT1/2 in NSCLC

Check if the same lab product or an alternative is used in the 5 most similar protocols
The siGENOME siRNAs for the human HIF1α were obtained from Dharmacon (Lafayette, CO). AKT1/2 siRNA were purchased from Cell Signaling. H2228 or H3122 were transfected with siRNAs using DharmaFECT 1 according to the manufacturer (Dharmacon). Twenty-four hours after transfection, cells were incubated with fresh complete medium for another 48 hours before protein and mRNA analysis.
Ma Y., Yu C., Mohamed E.M., Shao H., Wang L., Sundaresan G., Zweit J., Idowu M, & Fang X. (2016). A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer. Oncogene, 35(47), 6132-6142.
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