Fmoc ser tbu oh

Manufactured by GL Biochem

Sourced in China

Fmoc-Ser(tBu)-OH is a protected amino acid commonly used in solid-phase peptide synthesis. It consists of the amino acid serine with a tert-butyl protecting group on the side chain and an Fmoc protecting group on the amino terminus.

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Lab products found in correlation

Fmoc lys boc oh, by GL Biochem (2 mentions) Fmoc arg pbf oh, by GL Biochem (2 mentions) Fmoc tyr tbu oh, by GL Biochem (2 mentions) Fmoc asn trt oh, by GL Biochem (2 mentions) Fmoc ile oh, by GL Biochem (2 mentions) Fmoc phe oh, by GL Biochem (2 mentions) Silver nitrate agno3, by Merck Group (1 mentions) Trisodium citrate, by Merck Group (1 mentions) N n diisopropylethylamine, by Merck Group (1 mentions) Thioflavin t, by Merck Group (1 mentions) N n diisopropylcarbodiimide, by Merck Group (1 mentions) Fmoc leu, by GL Biochem (1 mentions) Fmoc gly, by GL Biochem (1 mentions) Fmoc trp boc oh, by GL Biochem (1 mentions) Nonadecanoic acid, by Merck Group (1 mentions) Fmoc his trt oh, by GL Biochem (1 mentions) Fmoc pro oh, by GL Biochem (1 mentions) Matrix metalloproteinase 9 mmp 9, by Merck Group (1 mentions) Piperidine, by Iris Biotech (1 mentions) Trifluoroacetic acid tfa, by Iris Biotech (1 mentions)

Spelling variants of this product

Fmoc-Ser (2 citations)

2 protocols using fmoc ser tbu oh

Peptide Synthesis and Characterization

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The conventional amino acids, Fmoc-Ala, Fmoc-Lys(Boc)-OH, Fmoc-Arg(Pbf)-OH, Fmoc-Gly, Fmoc-His(Trt)-OH, Fmoc-Leu, Fmoc-Ser(tBu)-OH, Fmoc-Thr(OtBu)-OH, Fmoc-Trp(Boc)-OH, Fmoc-Tyr(tBu)-OH, Fmoc-Asn(Trt)-OH, Fmoc-Ile-OH, Fmoc-Phe-OH, Fmoc-Cys(Trt)-OH, Fmoc-Pro-OH, were acquired from GL Biochem Ltd. (Shanghai, China). N,N′-diisopropylcarbodiimide (DIC), Oxyma pure, 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate (HATU), N,N-Diisopropylethylamine, triisopropylsilane (TIS), 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP), nonadecanoic acid (C19) were purchased from Sigma-Aldrich (Italy). Rink amide p-methylbenzhydrylamine (MBHA) resin, Fmoc-L-Lys(Mtt)-OH, piperidine, and trifluoroacetic acid (TFA) were purchased from Iris Biotech GmbH (Marktredwitz, Germany). Anhydrous solvents [N,N-dimethylformamide (DMF) and dichloromethane (DCM)], Doxo-EMCH, matrix metalloproteinase-9 (MMP-9) and dialysis tubing benzoylated, Nile Red, and Thioflavin T were purchased from Sigma-Aldrich (Milan, Italy). Silver nitrate (AgNO₃), and trisodium citrate were obtained from Sigma-Aldrich (Luzais, Saint-Quentin-Fallavier, France). Ultrapure water was produced using a Barnstead EASYpure RoDi system (Thermo Fisher Scientific, Villebon sur Yvette, France). All chemicals and reagents were of analytical grade and used as received.

Del Genio V., Falanga A., Allard-Vannier E., Hervé-Aubert K., Leone M., Bellavita R., Uzbekov R., Chourpa I, & Galdiero S. (2022). Design and Validation of Nanofibers Made of Self-Assembled Peptides to Become Multifunctional Stimuli-Sensitive Nanovectors of Anticancer Drug Doxorubicin. Pharmaceutics, 14(8), 1544.

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Solid-Phase Peptide Synthesis Protocol

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PL-Wang resin (0.4 mmole/g) was obtained from Varian, Inc. (Shropshire, UK). Fmoc-Ser(tBu)-OH, Fmoc-Met-OH, Fmoc-Leu-OH, Fmoc-Ile-OH, Fmoc-Ala-OH, Fmoc-Lys(Boc)-OH, Fmoc-Asp(OtBu)-OH, Fmoc-Asn(trt)-OH, Fmoc-Glu(OtBu)-OH, Fmoc-Phe-OH, Fmoc-Gln(trt)-OH, Fmoc-Tyr(tBu)-OH, Fmoc-Arg(pbf)-OH, N,N′-diisopropylcarbodiimide (DIC), 4-dimethylaminopyridine (DMAP) and triisopropylsilane (TIS) were obtained from GL Biochem Ltd. (Shanghai, China). Fmoc-Val-OH, Fmoc-Gly-OH, Fmoc-His(trt)-OH and N,N,N′,N′-tetramethyl-uronium-hexafluoro-phosphate (HBTU) were obtained from CS Bio Co. (Menlo Park, USA). Dimethylformamide (DMF), dichloromethane (DCM) and dimethyl sulfoxide (DMSO) were obtained from Daejung Chemicals & Metals Co., Ltd. (Siheung, Korea). Anisole, piperidine and N,N-diisopropylethylamine (DIEA) were obtained from Sigma-Aldrich (St. Louis, USA). Trifluoroacetic acid (TFA) was obtained from Yakuri Pure Chemicals Co., Ltd. (Kyoto, Japan). Ether, Anhydrous was obtained from J.T. Baker (Center Valley, USA). Zoletil® (Virbac) and Rompun® (Bayer Parma) were obtained from SMP animal medicine (Suwon, Korea). Protease inhibitor cocktail was obtained from Roche Diagnostics (IN, USA). EDTA treated BD vacutainer® was obtained from Becton, Dickinson and Company (NJ, USA). Human Aβ42 Ultrasensitive ELISA kit was obtained from Invitrogen (CA, USA).

Cho S.M., Kim H.V., Lee S., Kim H.Y., Kim W., Kim T.S., Kim D.J, & Kim Y. (2014). Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model. Scientific Reports, 4, 6777.

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