Aplio xg ssa 790a

Our database consisted of 578 breast ultrasonographic images. The lesion sizes in our database were 4–25 mm. These images were obtained from 566 patients using an ultrasound diagnostic system (APLIO™ XG SSA-790A, Toshiba Medical Systems Corp., Otawara, Tochigi Prefecture, Japan) with a 12 MHz linear-array transducer (PLT-1204AT) at Mie University Hospital in 2010. All cases had already been pathologically proven. After the diagnosis of benign cases was confirmed by fine-needle aspiration, the patients were examined again at 6 to 12 months after the initial diagnosis. To avoid the influence of artifacts in the CNN analysis, cases that had undergone a vacuum-assisted needle biopsy, excisional biopsy, or received medication were excluded in this study. The sizes of the images were 716 × 537 pixels with 8-bit grayscale. The database included 287 malignant lesions (217 invasive carcinomas and 70 noninvasive carcinomas) and 291 benign lesions (111 cysts and 180 fibroadenomas). The histological classifications for all lesions were proved by pathologic diagnosis. Regions of interest (ROIs) which included a whole lesion were selected from ultrasonographic images by experienced clinicians. Those ROIs were used for the input of our CNN model. Figure 1 shows an example of lesions with four different types of histological classifications.

Ultrasound images of carotid plaques were collected by a sonographer that has 5 years of experience in vascular imaging using an Aplio XG (SSA-790A) (Toshiba Medical Systems, Japan) equipped with a 5–12 MHz linear-array transducer (PLT-805AT). The carotid artery was examined with the head tilted slightly upward in the mid-line position. The transducer was manipulated so that the near and far walls were parallel to the transducer footprint, and the lumen diameter was maximized in the longitudinal plane.
According to the criteria of the European carotid plaque study group, plaques were classified into three different types: echolucent, intermediate and echo-rich plaques [12 (link)]. The visual classification of plaque echogenicity was independently performed by two sonographers with at least 5 years of experience in vascular imaging, and a kappa value (κ) was calculated to evaluate the between-observer agreement.

We assessed carotid Atherosclerosis by a Color Doppler ultrasound system (Aplio XG SSA-790A; Toshiba Medical Systems Corporation, Tokyo, Japan), including carotid intima-media thickness (CIMT) and plaque Crouse score. The judgment criteria are that in longitudinal sections, CIMT value: ≤1.0 mm was considered to be healthy, >1.0 mm indicates the formation of carotid atherosclerosis. We used Crouse scoring to assess plaques. The judgment criterion of Crouse scoring is the maximum thickness (millimeter) of each plaque. The sum of the bilateral maximum CIMT values was calculated to determine Crouse score. If the CIMT value ≤1.2 mm, the Crouse score was 0. Physicians who were unaware of the clinical data recorded Carotid ultrasonography data.

In vitro acoustic activity of NBs internalized cells was assessed using a clinical US scanner (AplioXG SSA-790A, Toshiba Medical). To carry out the measurements, cells (~ 2x 10⁶) were washed and detached using trypsin. Following detachment and resuspension in PBS, the cell suspension was placed in a custom-made 1.5% (w/v) agarose phantom 37 (link). The phantom was affixed over a 12 MHz linear array transducer, and images were acquired with contrast harmonic imaging (CHI) at 0.1 mechanical index (MI), 65 dynamic range, 70 dB gain, and 0.2 frames/sec imaging frame rate. Using onboard software, a region of interest (ROI) analysis was performed on all samples to measure the mean signal intensity in each ROI.39 (link) The data were then exported to Microsoft Excel for further processing. The experiments were carried out in triplicate.

The thyroid US evaluation was performed with linear high frequency probes (TOSHIBA Aplio XG™ SSA790A, − 9 to 13 MHz). Nodules were classified according to the Thyroid Imaging Reporting and Data System Classification (TIRADS) [16 (link)]. Fine-needle aspiration cytology (FNAC) with a 27-gauge needle was performed if nodule was: 1) TIRADS 5 and > 5 mm, 2) TIRADS 4B and > 7 mm, 3) TIRADS 4A and > 10 mm, 4) TIRADS 3 and > 20 mm. We analyzed the FNAC using the Bethesda (2010) classification.