Jmp pro ver 15

In this study, disease recurrence after surgery was classified into three categories: “local-only,” “distant-only,” and “simultaneous.” Local recurrence was defined as intrapelvic recurrence detected using imaging modalities, including LPLN recurrence and anastomotic recurrence. Distant metastasis was defined as disease recurrence that had spread to remote organs (e.g., the lung, liver, peritoneum, and remote lymph nodes). Only the first disease recurrence in each LARC patient was assessed. Recurrence-free survival (RFS), overall survival (OS), and cumulative incidence of recurrence were plotted using the Kaplan-Meier method. The OS was measured from date of surgery to death. The cumulative incidence of recurrence was assessed in the patients with disease recurrence. Surgically resectable recurrence was defined as a lesion resected with curative-intent, regardless of the use of systemic chemotherapy and/or radiotherapy prior to resection. Best supportive care and/or systemic palliative chemotherapy following disease recurrence was defined as an “unresectable case.” Fisher’s exact test and log-rank tests were used to assess statistical significance (P<0.05) for categorical and survival data, respectively. All statistical analyses were performed by RO using JMP Pro ver.15 (SAS Institute, Cary, NC, USA).

All continuous variables were checked for normality with the Kolmogorov–Smirnov test. Age, height, weight, BMI, NRS, IFP thickness value, and change in IFP thickness were compared using the t-test or the Mann–Whitney U test. Fisher’s exact test was used for sex comparisons between the AKP and control groups. In addition, Spearman’s rank correlation coefficient was used to examine the correlation between the change in IFP thickness and the NRS score on the reconstructed knee. Quantitative variables are expressed as means ± standard deviations and qualitative variables as frequencies. JMP^® Pro Ver. 15 (SAS) was used for all analyses, and the significance level was set at < 5%.

Values under the detection limits were recorded as half of the detection limit. The urinary concentrations were normalized to urinary creatinine amounts (g-Cr). To enable a statistical analysis comparison, the urinary concentrations were transformed into common logarithmic values because the distributions were not normal. EQPs were defined according to the criteria proposed by Ideno et al. [18 (link)]: log(equol/daidzein) ≥ −1.42 indicates EQP status, and log(equol/daidzein) < −1.42 indicates non-EQP status.
Urinary zinc concentrations between EQP and non-EQP were compared by Student’s t-test. To adjust the potential confounders (age, BMI, etc.), we conducted multivariable regression analyses. Records with missing values were excluded from the main analyses while the missing values (smoking: 19, menstrual status: 13) were processed by single imputation methods (mode imputations) as additional analyses. JMP Pro (ver. 15; SAS Institute, Cary, NC) was used to perform these calculations. The alpha level for all tests was 0.05.