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Elition

Manufactured by Philips
Sourced in Germany

The Philips Elition is a versatile lab equipment designed for a variety of scientific applications. It features a core function of providing accurate and reliable measurements, but a detailed description cannot be provided while maintaining an unbiased and factual approach without further interpretation or extrapolation.

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13 protocols using elition

1

Multimodal Brain Imaging Protocol

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MRI examinations were performed using a 1.5-T (Intera, Philips Healthcare, Best, Netherlands; and Magnetom Amira, Siemens, Germany) or 3.0-T scanner (Achieva, Ingenia, or Elition, Philips Healthcare; and Vida, Siemens) with an 8- or 32-channel head coil. The MRI parameters for the 3D gradient echo sequence were as follows: field of view (FOV), 240 × 240 mm2; acquisition matrix, 240 × 240; slice thickness, 1 mm; number of excitations, 1; repetition time (TR), 8–10.6 ms; echo time (TE), 3.7–5.7 ms; and flip angle, 8°. The MRI parameters for the 3D turbo spin-echo sequence with the black blood technique were as follows: FOV, 240 × 240 mm2; acquisition matrix, 240 × 240; slice thickness, 1 mm; number of excitations, 1; TR, 500 ms; TE, 30 ms; and flip angle, 90°. For contrast enhancement, gadobutrol (Gadovist®, Bayer Schering Pharma AG, Berlin, Germany; 0.1 mmol/kg) was injected intravenously.
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2

Structural Brain Imaging with 3T MRI

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MRI scans were performed using a 3.0 Tesla Philips scanner (Intera, CX, Achevia, and Elition models) and 32-channel head coil. Structural images were collected using a sagittal magnetization prepared gradient-echo (MPRAGE) sequence: repetition time /echo time = 6.9/3.3 ms; field of view = 240 × 240; 170 slices; slice thickness 1.0 mm; 0 mm gap; flip angle = 8 degrees; voxel size = 0.75 × 0.75 × 1.0 mm. Total scan duration was 6 min.
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3

MRI of Lower Leg Muscle During Plantarflexion

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MR datasets were acquired in the right lower leg on a 3 Tesla MR System (Philips Elition; Best, the Netherlands) using a 16-element receiver coil (anterior) and the 10-element receiver coil built into the patient table (posterior). The participants were positioned supine, feet-first in the MR scanner with the right leg as close as possible to the centre of the bore. The foot was placed in an MR compatible exercise device which could be fixed in ankle angles ranging from +25° degrees plantarflexion to −15° degrees dorsiflexion. The anterior coil was placed on top of the legs and supported with foam pillows and fixation bands to ensure that the coil covered the full lower leg, did not compress the muscle, and did not move during the change of foot position from plantarflexion (+20°) to dorsiflexion (−10°). MRI data were first acquired with the foot passively held at +20° and again after the foot was passively rotated to −10°. The MR examination consisted of:
For each type of sequence, the superior end of the slice stack was positioned at the level of the tibia plateau and the image stacks were rotated to align their midpoint with the tibia bone.
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4

3D MRI for Periodontal Bone Assessment

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Patients were examined with a 3-T MRI scanner (Elition, Philips Healthcare) at the Department of Diagnostic and Interventional Neuroradiology, Technical University Munich, using a 16-channel Head Neck Cervical Spine Array. No additional surface coil was used. Patients were positioned head-first in a supine position. The sequencing protocol consisted of a short survey for sequence position planning (acquisition time 0:39 min), a 3D isotropic T2-weighted STIR sequence, and a 3D isotropic Fast Field Echo (FFE) T1-weighted Black bone sequence (acquisition time 5:31 min). Detailed imaging parameters are summarized in the Suppl. Tab. S1. 3D T1 bone sequence served to determine changes within the tooth-supporting alveolar bone associated with periodontitis.
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5

Motion-Corrected Hepatic Imaging Using Eovist

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Data were acquired using a T1-weighted stack-of-stars acquisition with golden-angle rotation (111.25o) between consecutive radial lines. No acceleration was performed along the Cartesian kz dimension, and the pulse sequence encoded all kz points for one angle and then moved to the next angle, resulting in continuous data acquisition during offline motion dictionary learning. The first three patients were scanned on a 3T MRI scanner (Philips Ingenia, Best, The Netherlands) without contrast agent injection. The last two patients were scanned on a different 3T MRI scanner (Philips Elition, Best, The Netherlands) after contrast agent (Eovist) injection. Manual intravenous injection of ~10 mL (depending on patient’s weight) of Eovist was performed 30 minutes before acquisition to image the hepatobiliary phase. A 12channel posterior and 16-channel anterior coil array was employed. All 5 patients were imaged with a FOV of 358×358×256 mm3, voxel size of 1.4×1.4×4 mm3, a TR of 4 ms and TE of 2 ms. Table 1 shows relevant imaging parameters for these 5 patients that are different.
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6

Quantifying Abdominal and Pelvic Skeletal Muscle

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MRI examinations of the abdomen and pelvis were performed on a 3T scanner (Elition; Philips Healthcare, Best, Netherlands). Subjects were placed in supine position and a combination of anterior and posterior coil arrays was used. Total scan time was reduced to a minimum (total scan time of 5 to 7 min) and embedded in the patient’s regular clinical follow-up schedule.
To measure PDFF and volume of skeletal muscle, a six-echo multi-echo gradient echo sequence with bipolar gradients was used. Four stacks covered the abdomen and pelvis from the liver dome to the femoral heads. Sequence parameters are shown in Table 1. Complex-based water–fat separation was performed. Specifically, PDFF maps were generated using the vendor’s online complex-based water–fat quantification algorithm, accounting for known confounding factors including the presence of multiple fat peaks, a single T2* correction and eddy-current-induced phase errors.
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7

Multiparametric MRI Imaging Protocol for Prostate Cancer

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Imaging was performed using a 3.0 T scanner (Elition, Philips Healthcare, Best, The Netherlands) with a 32-channel phased-array surface coil. All participants were instructed to urinate 2 h before the MRI examination and were not allowed to drink or urinate thereafter until examination completion. The MR protocol comprised the following sequences: T2-weighted fast spin echo sequence, DWI, axial T2 mapping, and T1-weighted three-dimensional spoiled gradient echo dynamic contrast-enhanced (DCE) sequence after Gadoteridol injection. For DWI, three b-values (b = 0, 800, and 1000 s/mm2) were acquired, and ADC maps were calculated using b = 0 and b = 1000. Axial T2-mapping images were acquired using the T2-prepared single-shot True FISP. The detailed scan parameters are listed in Table S1. The total MRI acquisition time was approximately 40 min.
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8

Multimodal Brain Imaging Protocol

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MRI scans were acquired at the University of British Columbia MRI Research Centre on 3.0 T Phillips Achieva or Elition scanners (Philips Healthcare, Best, The Netherlands), with parallel imaging and an eight-channel and thirty-two-channel sensitivity encoding head coil, respectively. We acquired the following structural scans: 1) a 3D magnetization-prepared rapid gradient-echo (MPRAGE) T1 anatomical scan (repetition time (TR)/time to echo (TE)/inversion time (TI) = 3000/3.7/905 ms, flip angle = 9°, voxel size = 1 mm isotropic, field of view (FOV) = 256 × 224 × 180 mm), 2) a fluid attenuated inversion recovery (FLAIR) scan acquired in the axial plane (TR/TE/TI = 9000/90/2500 ms, flip angle = 90°, voxel size = 0.94 × 0.94 mm FOV = 240 × 191 × 144 mm, slice thickness = 3 mm), and 3) a combined T2-weighted (T2) and proton density (PD) scan acquired in the axial plane (TR/TE1/TE2 = 2500/9.5/90 ms, flip angle = 90°, voxel size = 0.94 × 0.94 mm, FOV = 240 × 191 × 144 mm, slice thickness = 3 mm). For DTI data, a 3D high-angular resolution diffusion imaging (HARDI) scan was acquired across 60 non-collinear diffusion gradients (b-value = 700 s/mm2, TR/TE = 7094/60 ms, voxel size = 2 mm, FOV = 224 × 224 × 154 mm, slice thickness = 2.2 mm), along with two unweighted (b0) diffusion volumes.
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9

Functional MRI Preprocessing Pipeline

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Imaging data were acquired on a 3T full-body scanner (Phillips Elition) with a 20-channel head coil using a T2*-weighted echo planar imaging (EPI) pulse sequence (TR 1500 ms, TE 30 ms, flip angle 70 °, whole-brain coverage 28 slices of 3 mm thickness, in-plane resolution 3 by 3 mm, FOV 240 by 205.71 mm). Preprocessing was performed in FSL, including slice time correction, motion correction, linear detrending, high-pass filtering (140 s cutoff), and coregistration and affine transformation of the functional volumes to a template brain (MNI). Functional images were resampled to 3 mm isotropic voxels for all analyses.
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10

Cardiac MRI Protocol for Myocardial Evaluation

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All patients underwent examination using a 3.0 T MR scanner (Elition, Philips Healthcare, Andover, the Netherlands) with a 32-channel abdominal coil. The imaging protocol included chest-lead electrocardiographic gating, respiratory gating, and breath-holding at the end of expiration to acquire images. Two-, three-, and four-chamber views, along with short-axis views, were obtained using the steady-state free precession (SSFP) sequence. The short-axis series was scanned continuously from basal to apical segments under the following scanning parameters: repetition time (TR) =43 ms, echo time (TE) =1 ms, field of view (FOV) =320 mm × 320 mm, and slice thickness =8 mm. LGE imaging was obtained at 10–15 minutes postcontrast using an inversion recovery-prepared T1-weighted gradient echo sequence with an inversion time via the Look-Locker sequence. The scanning parameters for delayed enhancement images were as follows: TR =6.1 ms, TE =3 ms, FOV =320 mm × 320 mm, and slice thickness =8 mm.
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