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Guanfacine hydrochloride

Manufactured by Bio-Techne
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Sourced in United Kingdom

Guanfacine hydrochloride is a synthetic organic compound used as a chemical reagent in research and laboratory settings. It functions as an alpha-2 adrenergic receptor agonist. The core function of guanfacine hydrochloride is to serve as a pharmacological tool for studying the alpha-2 adrenergic receptor and its associated physiological processes.

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Lab products found in correlation

Yohimbine hydrochloride, by Bio-Techne (1 mentions) Prazosin hydrochloride, by Bio-Techne (1 mentions) Terazosin, by Bio-Techne (1 mentions) Clonidine hydrochloride, by Bio-Techne (1 mentions) Idazoxan hydrochloride, by Bio-Techne (1 mentions) Efaroxan hydrochloride, by Bio-Techne (1 mentions) Rauwolscine hydrochloride, by Bio-Techne (1 mentions) Rx821002, by Bio-Techne (1 mentions) Brl44408, by Bio-Techne (1 mentions) Uk14304, by Bio-Techne (1 mentions) Jp1302, by Bio-Techne (1 mentions) Wb4101, by Bio-Techne (1 mentions) Dexmedetomidine hydrochloride, by Bio-Techne (1 mentions) Guanabenz acetate, by Bio-Techne (1 mentions)

2 protocols using guanfacine hydrochloride

1

Guanfacine Hydrochloride Administration Protocol

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Guanfacine hydrochloride was purchased from Tocris (Abingdon, UK), dissolved in 0.9% saline and injected i.p. in a volume of 10 mL·kg−1 throughout.
Pillidge K., Porter A.J., Dudley J.A., Tsai Y.C., Heal D.J, & Stanford S.C. (2014). The behavioural response of mice lacking NK1 receptors to guanfacine resembles its clinical profile in treatment of ADHD. British Journal of Pharmacology, 171(20), 4785-4796.
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2

Pharmacological Agents for Neuroscience Research

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ARC-239, BRL-44408, clonidine hydrochloride, dexmedetomidine hydrochloride, efaroxan hydrochloride, guanabenz acetate, guanfacine hydrochloride, idazoxan hydrochloride, JP-1302, prazosin hydrochloride, rauwolscine hydrochloride, RS-79948, RX-821002, terazosin, UK-14304, WB-4101 and yohimbine hydrochloride were acquired from Tocris (Ellisville, MO). Atipamezole was from Orion Corporation (Espoo, Finland) and isoflurane was from Abbott Diagnostics (Chicago, IL). All other chemicals were obtained from Sigma-Aldrich (St. Louis, MO).
Biggane J.P., Xu K., Goldenstein B.L., Davis K.L., Luger E.J., Davis B.A., Jurgens C.W., Perez D.M., Porter J.E, & Doze V.A. (2022). Pharmacological characterization of the α2A-adrenergic receptor inhibiting rat hippocampal CA3 epileptiform activity: Comparison of ligand efficacy and potency. Journal of receptor and signal transduction research, 42(6), 580-587.
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