Compounds were purchased as follows: decitabine from Wako Pure Chemical Industries, Ltd. (Osaka, Japan); cisplatin, doxorubicin and Q-VD-OPh from Calbiochem (San Diego, CA, USA); paclitaxel from Sigma-Aldrich; and hydroxychloroquine and necrostatin-1 from Cayman Chemical (Ann Arbor, MI, USA). Stock solutions of decitabine were prepared in dimethyl sulfoxide (DMSO; Sigma-Aldrich) at concentrations of 0.5 and 1 mM.
Decitabine
Manufactured by Fujifilm
Sourced in Japan
Decitabine is a chemical compound used in laboratory research and testing. It functions as a DNA methyltransferase inhibitor, which can be utilized for various experimental purposes. The core function of Decitabine is to inhibit DNA methylation, a process that can have implications in areas such as epigenetics and cell biology.
Automatically generated - may contain errors
Lab products found in correlation
Hydroxychloroquine, by Cayman Chemical (1 mentions)
Decitabine, by Merck Group (1 mentions)
Necrostatin 1, by Cayman Chemical (1 mentions)
Paclitaxel, by Merck Group (1 mentions)
Dimethyl sulfoxide (dmso), by Merck Group (1 mentions)
Chloroform, by Fujifilm (1 mentions)
Cytarabine, by Tokyo Chemical Industry (1 mentions)
Mycophenolate mofetil, by Merck Group (1 mentions)
Ammonium hydroxide solution, by Merck Group (1 mentions)
Dimethyl sulfoxide (dmso), by Fujifilm (1 mentions)
Acetonitrile, by Fujifilm (1 mentions)
High performance liquid chromatography, by Fujifilm (1 mentions)
Phosphate buffered saline (pbs), by Thermo Fisher Scientific (1 mentions)
Hplc grade methanol, by Fujifilm (1 mentions)
Ammonium bicarbonate, by Merck Group (1 mentions)
2 protocols using decitabine
1
Compound Acquisition and Stock Preparation
2
Analysis of Antimetabolite Drug Compounds
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Mycophenolic acid, azacitidine, decitabine, 5‐FU, IMP disodium salt, GTP, high‐performance liquid chromatography (HPLC) grade methanol, acetonitrile (ACN), dimethyl sulfoxide (DMSO), and chloroform were purchased from Wako Pure Chemical Industries (Osaka, Japan). 5‐Azacytidine 5′‐triphosphate (aza‐CTP) ammonium salt was purchased from American Biochemicals (San Diego, CA, USA). Cytarabine and 2′‐deoxy‐2′‐fluorocytidine hydrate (2D2F) were purchased from Tokyo Chemical Industry (Tokyo, Japan). FF‐10501‐01 (3/4 hydrate of FF‐10501) and FF‐10501RMP disodium salt were provided by Toyama Chemical (Tokyo, Japan). Gemcitabine hydrochloride was purchased from Teva Pharmaceutical Industries (Netanya, Israel). Mycophenolate mofetil, ammonium bicarbonate, and ammonium hydroxide solution were purchased from Sigma‐Aldrich (St. Louis, MO, USA). Phosphate‐buffered saline (PBS) was purchased from Life Technologies (Gaithersburg, MD, USA).
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