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Poly vinyl alcohol or pva

Manufactured by Merck Group
Sourced in United Kingdom

Poly(vinyl alcohol) or PVA is a synthetic, water-soluble polymer. It is a colorless, odorless, and nontoxic material commonly used in a variety of industrial and laboratory applications. PVA's core function is to provide a versatile material with properties such as film-forming, emulsifying, and stabilizing abilities.

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2 protocols using poly vinyl alcohol or pva

1

PLGA-Paclitaxel Nanoparticle Formulation

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Poly-lactide-co-glycolide (PLGA) polymers were purchased from Boehringer Ingelheim (Ingelheim, Germany), paclitaxel from Hande Tech (Houston, TX), lipids (1,2-dioleoyl-3-trimethylammoniumpropane or DOTAP, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine or DOPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] or DSPE-PEG, cholesterol) from Avanti Polar Lipids, Inc. (Alabaster, AL, USA), cefotaxime sodium from Hoechst-Roussel (Somerville, NJ), poly(vinyl alcohol) or PVA from Sigma Chemical (St. Louis, MO), chromatography solvents from Fisher Scientific (Fair Lawn, NJ), gentamicin from Solo Pak Laboratories (Franklin Park, IL), and all other cell culture supplies from Life Technologies (Grand Island, NY). Survivin siRNA (siSurvivin, human specific, #6351), survivin monoclonal antibody (71G4B7E), and caspase-3 polyclonal antibody (#9661) were purchased from Cell Signaling Technology (Danvers, MA), survivin polyclonal antibody (C-19, sc-8807) from Santa Cruz Biotechnology (Santa Cruz, CA), and Ki67 (MM1 clone) antigen kit from Novocastra Lab (Newcastle, UK). All chemicals and reagents were used as received.
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2

Cabotegravir Nanosuspension Formulation

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Long-acting cabotegravir (CAB LA) nanosuspension vials for IM injection with drug content (400 mg/2 mL) and micronized powders of CAB Na were supplied by ViiV Healthcare (Research Triangle Park, NC, USA). Poly(vinyl alcohol), or PVA, of molecular weight (MW) 9 to 10 kDa, 80% hydrolyzed (PVA 10K), and of MW 31 to 50 kDa, 87% to 89% hydrolyzed (PVA 50K), were purchased from Sigma–Aldrich (Dorset, UK). Poly(vinyl pyrrolidone) K29-32 gel (MW 58 kDa) was a gift from Ashland (Kidderminster, UK). Liquid silicone elastomer mix was purchased from Nusil Technology (Buckinghamshire, UK). Ultrapure water was obtained from a water purification system (Elga PURELAB® DV 25, Veolia Water Systems, Dublin, Ireland). All other chemicals and materials were of analytical reagent grade and supplied by Sigma–Aldrich.
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