Au480 automatic chemistry analyzer

Manufactured by Beckman Coulter

Sourced in United States

The AU480 is an automatic chemistry analyzer designed for clinical laboratories. It performs a wide range of routine clinical chemistry tests, including colorimetric, enzymatic, and immunoassay analyses. The AU480 is capable of processing a high volume of samples efficiently and accurately.

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Lab products found in correlation

Cm1860 cryostat, by Leica (2 mentions) Blood glucose meter, by Roche (2 mentions) Adhesion microscope slides, by Thermo Fisher Scientific (1 mentions)

Spelling variants of this product

AU480 (221 citations) AU480 Chemistry Analyzer (113 citations) AU480 analyzer (29 citations) Automatic analyzer (16 citations) Automatic chemistry analyzer (8 citations) AU480 Automatic (2 citations)

2 protocols using au480 automatic chemistry analyzer

Kidney tissue analysis protocol

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The FBG was determined using a blood glucose meter (Roche, Basel, Switzerland). Glycosylated hemoglobin (HbA1c) was detected with a Quo-Test HbA1c Analyzer (QUOTIENT Diagnostics Ltd. Walton-on-Thames, Surrey, UK). The urine creatinine and urea nitrogen were measured using an AU480 automatic chemistry analyzer (Beckman Coulter Inc., Brea, CA, USA).
The frozen kidney tissues were cut into 8 μm serial sections at −22 °C using a Leica CM1860 cryostat (Leica Microsystems Ltd., Wetzlar, Germany) and mounted onto adhesion microscope slides (Thermo Scientific, CA, USA). Hematoxylin and eosin (H&E) staining of kidney sections was performed to reveal the histopathological lesions.

Zhang X., Liu Y., Yang S., Gao X., Wang S., Wang Z., Zhang C., Zhou Z., Chen Y., Wang Z, & Abliz Z. (2023). Comparison of Local Metabolic Changes in Diabetic Rodent Kidneys Using Mass Spectrometry Imaging. Metabolites, 13(3), 324.

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Comprehensive Renal Function Analysis

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FBG levels were measured using a blood glucose meter (Roche, Basel, Switzerland). Glycosylated hemoglobin (HbA1c) concentrations were measured using a Quo-Test HbA1c Analyzer (QUOTIENT Diagnostics Ltd. Walton-on-Thames, Surrey, UK).
The blood biochemical parameters including urea nitrogen, creatinine, uric acid, total cholesterol, glucose, and triglyceride levels were determined using an AU480 automatic chemistry analyzer (Beckman Coulter Inc., Brea, CA, USA). Urinary creatinine, K⁺, Na⁺, Cl⁻, and Ca²⁺ concentrations were also determined using the AU480 automatic chemistry analyzer.
Frozen renal sections (10 μm) were prepared on a CM1860 cryostat (Leica Microsystems Ltd., Wetzlar, Germany) at −18 °C and mounted onto adhesion microscope slides. The H&E staining was used to examine the histopathological lesions of renal sections.

Wang Z., Fu W., Huo M., He B., Liu Y., Tian L., Li W., Zhou Z., Wang B., Xia J., Chen Y., Wei J, & Abliz Z. (2021). Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging. Acta Pharmaceutica Sinica. B, 11(11), 3665-3677.

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