Dpx 400 mhz high performance digital ft nmr spectrometer

¹H NMR (400 MHz) and ¹³C NMR (100 MHz) spectra were recorded with a Bruker instrument DPX-400 MHz High-performance Digital FT-NMR Spectrometer in CDCl3andDMSO-d6 as the solvent and with tetramethylsilane (TMS) as the internal Standard at 25 °C. Chemical shifts are expressed in terms of parts per million (ppm), and the d coupling constants are given in Hz. IR spectra were obtained as KBr pellets using a Mattson 1000 FT-IR spectrometer. The scan range was from 400 to 4000 cm1, and 128 scans were accumulated to get 4.0 cm1 resolution, and the DTGS KBr detector used to register the FT-IR spectra. Elemental analyses were performed on a Costech ECS 4010 analyzer. Melting points were determined in a capillary tube on a Gallen Kamp apparatus and uncorrected. Reactions were monitored by thin-layer chromatography (silica gel 60 F254). Reagents were obtained from Sigma and used as received and used without further purification.

¹NMR spectra were recorded on 400 MHz a Bruker instrument DPX-400 MHz High-Performance Digital FT-NMR spectrometer using CDCl₃ and DMSO-d₆ with tetramethylsilane (TMS) as the international Standard at 25 °C. ¹³ C NMR spectra recorded on 100 MHz instruments. Chemical shifts are reported in parts per million (δ) and the coupling constants are given in Hz. IR spectra were obtained as KBr pellets using a Matson 1000 FT-IR spectrometer. Melting points were determined in a capillary tube on a Gallenkamp apparatus and are uncorrected. Reactions were monitored by thin layer chromatography (silica gel 60 F254). All solvents were used after purification according to international standards.