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Reduced form of β nicotinamide adenine dinucleotide phosphate

Manufactured by Merck Group
Sourced in United States

Reduced form of β-nicotinamide adenine dinucleotide phosphate is a coenzyme that plays a crucial role in various metabolic processes. It serves as an electron carrier and reducing agent in numerous enzymatic reactions.

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2 protocols using reduced form of β nicotinamide adenine dinucleotide phosphate

1

Quantitative Analysis of Curcumin Interactions

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BUS, CUR, dextromethorphan (DEX), phenacetin (PHE), testosterone (TES), and the reduced form of β-nicotinamide adenine dinucleotide phosphate (NADPH; as a tetrasodium salt) were purchased from Sigma-Aldrich Co. The purity of CUR was 94%, and that of the other compounds was higher than 98%. Other chemicals were of reagent grade or high-performance liquid chromatography (HPLC) grade.
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2

Metformin and Verapamil Uptake Kinetics

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Metformin hydrochloride was donated from Daelim Pharmaceutical Company (Seoul, Korea). Verapamil hydrochloride, norverapamil, ipriflavone (internal standard (IS) for the high-performance liquid chromatography (HPLC) analysis of metformin) and propranolol (IS for the HPLC analysis of verapamil and norverapamil), the reduced form of β-nicotinamide adenine dinucleotide phosphate, tris(hydroxymethyl)-aminomethane (Tris) buffer and ethylenediamine tetraacetic acid were purchased from Sigma–Aldrich Corporation (St. Louis, MO, USA). HEK-293 cells overexpressing OCT1 (SLC22A1) and OCT2 (SLC22A2) were purchased from Corning Life Sciences (Corning, NY, USA). Other chemicals were of reagent or HPLC grade.
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