Human soluble icam 1

Manufactured by R&D Systems

Sourced in United Kingdom

Human soluble ICAM-1 is a recombinant protein that corresponds to the extracellular domain of the human Intercellular Adhesion Molecule 1 (ICAM-1). ICAM-1 is a cell surface glycoprotein that mediates cell-cell adhesion through interactions with its ligands, such as LFA-1 (CD11a/CD18). This protein can be used in various research applications involving cell adhesion and immune system processes.

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Lab products found in correlation

Vcam 1sandwich elisa kits, by R&D Systems (2 mentions)

Spelling variants of this product

ICAM-1 (116 citations) Soluble ICAM-1/VCAM-1 conjugated to human Fc (2 citations)

2 protocols using human soluble icam 1

Quantifying Soluble ICAM-1 and VCAM-1 Levels

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The ICAM-1 and VCAM-1 levels were measured using human soluble ICAM-1 and VCAM-1
sandwich ELISA kits (R&D Systems Europe Ltd.). ELISA procedures were
performed according to the manufacturer’s instructions. The intra- and
inter-assay CVs ranged from 3.7% to 5.2 % and 4.4% to 6.7%, respectively, for
ICAM-1, and from 2.3% to 3.6% and 5.5% to 7.8%, respectively, for VCAM-1. Values
were expressed as ng/mL.

Nádró B., Lőrincz H., Molnár Á., Szentpéteri A., Zöld E., Seres I., Páll D., Paragh G., Kempler P., Harangi M, & Sztanek F. (2021). Effects of alpha-lipoic acid treatment on serum progranulin levels and inflammatory markers in diabetic neuropathy. The Journal of International Medical Research, 49(5), 03000605211012213.

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Measuring Soluble ICAM-1 and VCAM-1 Levels

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The ICAM-1 and VCAM-1 levels were measured with use of human soluble ICAM-1 and VCAM-1 sandwich ELISA kits (R&D Systems Europe Ltd., Abington, England). ELISA procedures were carried out according to the manufacturer's instructions. The intra-assay CVs and inter-assay CVs were in the range 3.7-5.2% and 4.4-6.7% (ICAM-1), and 2.3-3.6% and 5.5-7.8% (VCAM-1), respectively. The values were expressed as ng/ml.

Sztanek F., Lőrincz H., Molnár Á., Szentpéteri A., Zöld É., Serés I., Páll D., Harangi M., Kempler P., & Paragh G. (2020). The effect of α-lipoic acid treatment on plasma asymmetric dimethylarginine, a biomarker of endothelial dysfunction in diabetic neuropathy. Archives of Medical Science.

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