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Tenofovir is a lab equipment product used for pharmaceutical and biochemical research. It is a nucleotide reverse transcriptase inhibitor (NtRTI) that inhibits the activity of HIV reverse transcriptase, an essential enzyme for viral replication.

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2 protocols using tenofovir

1

Chitosan-Based Nanoparticle Delivery System

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Maraviroc was purchased from Shanghai Yudiao Chemistry Technology Co Ltd. (Shanghai, China), Tenofovir and Sodium tripolyphosphate were supplied by Macklin Biochemical Co. Ltd. (Shanghai, China), Chitosan (Molecular weight of 100–180 kDa and 70–85% deacetylated) was supplied by Dideu Medichem Ltd. (China), MRS Agar was procured from HiMedia Laboratory Pvt. Ltd. (Mumbai, India) Milli Q water (Milli Q water purification system, Merck, Germany) was used for all the experiments. All other chemicals were of analytical grade and used as obtained from the suppliers.
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2

Poloxamer and Chitosan Nanoparticles for Antiretroviral Delivery

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Poloxamer 407 (Pluronic F127), poloxamer 188 (Pluronic F68), and chitosan were supplied by Dideu Medichem Ltd. (China). Maraviroc was purchased from Shanghai Yudiao Chemistry Technology Co Ltd. (Shanghai, China). Tenofovir was supplied by Macklin Biochemical Co. Ltd. (Shanghai, China). Sodium tripolyphosphate, Span 60, and Hydroxy propyl methyl cellulose were procured from Shanghai Macklin Biochemical Co. Ltd. (Shanghai, China). Soya bean oil was purchased from Sunola Foods Ltd. (Lagos, Nigeria).
Milli-Q water (Milli-Q water purification system, Merck, Germany) was used for all the experiments. All other chemicals were of analytical grade and used as obtained from the suppliers, without further modification.
Cell lines: HeLa cells and fetal bovine serum were purchased from Cell Lines Service GmbH, Germany. HIV-1 BaL and TZM-bl cells were obtained from Fisher Bioservices /NIH-ARP German town, MD, USA.
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