Soluble tissue factor

Manufactured by R&D Systems

Soluble tissue factor (sTF) is a laboratory product available from R&D Systems. It is a recombinant human protein that plays a key role in the initiation of the blood coagulation cascade.

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Lab products found in correlation

C reactive protein (crp), by Thermo Fisher Scientific (2 mentions) I fabp, by Hycult Biotech (2 mentions) Scd163, by R&D Systems (1 mentions)

2 protocols using soluble tissue factor

Multiplex Biomarker Profiling in Plasma

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Concentrations of IL-1β, IL-1Ra, IL-6, IL-8, IL-10, IL-12p40, IL-12p70, IL-15, IL-17, IL-18, CCL2, CCL3, CCL4, CCL5, CCL11, CXCL10, IFN-γ, TNF-α, TGF-β, platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF) (Bio-Plex, Bio-Rad, Hercules, CA), C-reactive protein (CRP) (eBioscience, San Diego, CA), sCD163, soluble tissue factor (sTF) (R&D Systems, Minneapolis, MN) and intestinal fatty acid binding protein (I-FABP) (Hycult Biotech, The Netherlands) were assessed in cryopreserved plasma samples maintained at −80 °C.

Silveira-Mattos P.S., Narendran G., Akrami K., Fukutani K.F., Anbalagan S., Nayak K., Subramanyam S., Subramani R., Vinhaes C.L., Souza D.O., Antonelli L.R., Satagopan K., Porter B.O., Sher A., Swaminathan S., Sereti I, & Andrade B.B. (2019). Differential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome. Scientific Reports, 9, 1502.

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Plasma Biomarkers in Infectious Diseases

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Concentrations of IL-1β, IL-1Ra, IL-6, IL-8, IL-10, IL-12p40, IL-12p70, IL-15, CCL2, CCL3, CCL4, CCL5, CCL11, CXCL10, IFN-γ, TNF-α, TGF-β, platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF) (Bio-Plex, Bio-Rad, Hercules, CA), C-reactive protein (CRP) (eBioscience, San Diego, CA), soluble (s) CD14, sCD163, soluble tissue factor (sTF) (R&D Systems, Minneapolis, MN) and intestinal fatty acid binding protein (I-FABP) (Hycult Biotech, The Netherlands) were assessed in cryopreserved plasma samples maintained at −80°C from patients in the Indian cohort. A smaller panel of biomarkers containing IL-6, IL-8, IL-10, IL-12p40, IFN-γ, TNF-α, CCL3, CCL4, CXCL10, sCD14, sCD163 and sTF was investigated in the South African cohort due to limitations in available plasma volume.

Andrade B.B., Singh A., Narendran G., Schechter M.E., Nayak K., Subramanian S., Anbalagan S., Jensen S.M., Porter B.O., Antonelli L.R., Wilkinson K.A., Wilkinson R.J., Meintjes G., van der Plas H., Follmann D., Barber D.L., Swaminathan S., Sher A, & Sereti I. (2014). Mycobacterial Antigen Driven Activation of CD14++CD16− Monocytes Is a Predictor of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome. PLoS Pathogens, 10(10), e1004433.

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