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Prizm v 6

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Prizm v.6.0 is a graphing and data analysis software developed by GraphPad. It provides tools for creating a variety of graph types, analyzing data, and performing statistical tests.

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Prizm (110 citations) Prizm 6 (51 citations)

4 protocols using prizm v 6

1

Statistical Analysis of Experimental Data

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Statistical analysis was performed using standard Student’s t tests with Mann-Whitney post hoc tests (for comparison of 2 groups) or one-way ANOVA with Kruskal-Wallis post hoc tests (for multiple group comparisons; GraphPad Prizm v.6.0). The data was presented as a mean ± SEM with significance noted as p < 0.05. Sample size for each experiment are displayed in the figure legends.
Javeed N., Her T.K., Brown M.R., Vanderboom P., Rakshit K., Egan A.M., Vella A., Lanza I, & Matveyenko A.V. (2021). Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes. Cell reports, 36(8), 109613.
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2

Examining Genetic Influences on Mice

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AUC differences were identified by Student's unpaired t-test or two-way ANOVA. Biochemical and histological comparisons between Cat-/- and WT mice were performed using a Student's unpaired t-test. Body weight differences were determined by two-way ANOVA with differences at each time point being analyzed using a Student's unpaired t-test. Statistical comparisons were conducted using Graphpad Prizm v 6.0 (La Jolla, CA). Statistical significance was defined as P < 0.05.
Heit C., Marshall S., Singh S., Yu X., Charkoftaki G., Zhao H., Orlicky D.J., Fritz K.S., Thompson D.C, & Vasiliou V. (2016). Catalase Deletion Promotes PreDiabetic Phenotype in Mice. Free radical biology & medicine, 103, 48-56.
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3

Statistical Analysis of Experimental Data

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Statistical analysis was performed using standard Student’s t tests with Mann-Whitney post hoc tests (for comparison of 2 groups) or one-way ANOVA with Kruskal-Wallis post hoc tests (for multiple group comparisons; GraphPad Prizm v.6.0). The data was presented as a mean ± SEM with significance noted as p < 0.05. Sample size for each experiment are displayed in the figure legends.
Javeed N., Her T.K., Brown M.R., Vanderboom P., Rakshit K., Egan A.M., Vella A., Lanza I, & Matveyenko A.V. (2021). Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes. Cell reports, 36(8), 109613.
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4

Glucose Tolerance Test in Mice

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Nine mo old WT and Cat-/- mice were fasted overnight with water available ad libitum. Mice were anesthetized by isofluorane inhalation. The tail was then nicked to allow initial collection (t = 0) of blood from the tail vein for measurement of fasting blood glucose. Fifteen % (w/v) D-glucose, prepared by dissolution in tap water and passage of the solution through a sterile filter, was administered intraperitoneally (1.5 g/kg). Blood was then sampled from the tail vein 15, 30, 60 and 120 min thereafter and glucose levels were determined using a glucometer (OneTouch Ultra, One Touch). The area under the curve (AUC) of the blood glucose concentration–time curve was calculated using Graphpad Prizm V 6.0 (La Jolla, CA).
Heit C., Marshall S., Singh S., Yu X., Charkoftaki G., Zhao H., Orlicky D.J., Fritz K.S., Thompson D.C, & Vasiliou V. (2016). Catalase Deletion Promotes PreDiabetic Phenotype in Mice. Free radical biology & medicine, 103, 48-56.
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