Antibodies against glp 1r

Manufactured by Santa Cruz Biotechnology

Sourced in United States

Antibodies against GLP-1R are research-grade reagents used to detect and study the Glucagon-Like Peptide-1 Receptor (GLP-1R) in biological samples. These antibodies are designed to specifically bind to and recognize the GLP-1R protein, enabling researchers to investigate its expression, localization, and function in various experimental systems.

Automatically generated - may contain errors

Lab products found in correlation

Bcl 2, by Santa Cruz Biotechnology (2 mentions) P iκbα, by Abcam (1 mentions) Il 1β, by Thermo Fisher Scientific (1 mentions) Thapsigargin tg, by Merck Group (1 mentions) Bcl2 associated x (bax), by Santa Cruz Biotechnology (1 mentions) Ly294002, by Cell Signaling Technology (1 mentions) Mmp 3, by Santa Cruz Biotechnology (1 mentions) Liraglutide, by Novo Nordisk (1 mentions) P mtor, by Abcam (1 mentions) Beclin 1, by Abcam (1 mentions) Lc3 2, by Cell Signaling Technology (1 mentions) Antibodies against lc3, by Cell Signaling Technology (1 mentions) Acetyl α tubulin, by Cell Signaling Technology (1 mentions) Antibodies against p62, by Abcam (1 mentions) Clinical grade liraglutide, by Novo Nordisk (1 mentions)

Spelling variants of this product

GLP-1R (9 citations)

2 protocols using antibodies against glp 1r

Liraglutide Modulates ER Stress and Inflammation

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Liraglutide was obtained from Novo Nordisk (Princeton, NJ, USA). The IL-1β was from Peprotech. Antibodies against GRP78, PDI, IκB-α, p-IκB-α, and collagen II were obtained from Abcam (Cambridge, MA, USA). Antibodies against CHOP, p65, cleaved-caspase3 and specific PI3K inhibitor (LY294002) were obtained from Cell Signaling Technology (Beverly, MA, USA). Antibodies against GLP-1R, MMP3, IL-6, TNF-α, Bax and Bcl-2 were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Thapsigargin (TG) and other reagents were obtained from Sigma unless noted otherwise.

Chen J., Xie J.J., Shi K.S., Gu Y.T., Wu C.C., Xuan J., Ren Y., Chen L., Wu Y.S., Zhang X.L., Xiao J., Wang D.Z, & Wang X.Y. (2018). Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat. Cell Death & Disease, 9(2), 212.

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Liraglutide-Induced Cellular Responses

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Clinical-grade liraglutide was obtained from Novo Nordisk (Princeton, NJ, USA). Antibodies against GLP-1R, Bax and Bcl-2 were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Antibodies against LC3, LC3-II and acetyl-α-tubulin were acquired from Cell Signaling Technologies (Danvers, MA, USA). Antibodies against P62, beclin-1, p-mTOR, mTOR, and caspase3 were purchased from Abcam (Cambridge, MA, USA). All other reagents were obtained from Sigma-Aldrich (St. Louis, MO, USA) unless specified otherwise.

Chen J., Wang Z., Mao Y., Zheng Z., Chen Y., Khor S., Shi K., He Z., Li J., Gong F., Liu Y., Hu A., Xiao J, & Wang X. (2017). Liraglutide activates autophagy via GLP-1R to improve functional recovery after spinal cord injury. Oncotarget, 8(49), 85949-85968.

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