A sample size of minimum 35 in each group was calculated using Open epi software, with the power of 80% and confidence interval of 95% based on the study by Borhazowal
et al.[12 ] Sample size was calculated to estimate the mean difference in cuff pressures and volumes between three groups (P, SG, AL) using standard deviation (SD) of 2 ml for mean volumes and SD 12 cm H
2O for mean pressures.[12 ] Considering a dropout of 10%, a total of 120 patients were enrolled in the study. [
Figure 2] Statistical analysis of the data was done using the software, IBM SPSS (Statistical Package for the Social Studies)
Statistics for Windows, version 20 (IBM Corp., Armonk, N.Y., USA). Continuous variables were summarized using mean (SD) and analyzed using a one-way ANOVA test. Categorical variables were summarized as proportions and analyzed using Pearson’s Chi-square/Fisher’s exact test. Posthoc analysis was done using one-way ANOVA test whenever applicable.
Satya Prakash M.V., Aravind C, & Mohan V.K. (2022). Comparative evaluation of three methods of endotracheal tube cuff inflation for adequacy of seal. Journal of Anaesthesiology, Clinical Pharmacology, 38(4), 588-593.