C57bl 6 cd45 2 thy1

Example 1

WT C57BL/6 CD45.2 Thy1.2 and BALB/c mice were obtained from Charles Rivers, France. WT C57BL/6 CD45.1, Rag2^−/−, Cxcr3^−/−, Ifnar1^−/−, Dpp4^−/−, Dpp4^−/−, Cxcl10^−/−, Ccr5^−/−, Pmel-1 Thy-1.1⁺Thy-1.1⁺, OT1 and FVB-Tg(CAG-luc) mice were bred in our mouse facility. Male Pmel-1 Thy-1.1⁺Thy-1.1⁺ mice were crossed with female Cxcr3^−/− Thy-1.2⁺Thy-1.2⁺, mice to obtain first generation males that were Pmel-1 Cxcr3^−/− Thy-1.1⁺Thy-1.2⁺. Mice used were 7-12 weeks old. For inhibition of DPP4 activity in vivo, mice were fed with chow (SAFE) formulated to contain 1.1% Sitagliptin (trade name Januvia, Merck). Sitagliptin food was administrated to mice before treatments, unless stated differently in the figure legend. Mice were maintained in a specific pathogen free facility and all experimental protocols were approved by the Comité d'Ethique pour l'Expérimentation Animate (The ethics committee for animal experimentation) Paris.

Example 1

WT C57BL/6 CD45.2 Thy1.2 and BALB/c mice were obtained from Charles Rivers, France. WT C57BL/6 CD45.1, Rag2^−/−, Cxcr3^−/−, Ifnar1^−/− Dpp4^+/−, Dpp4^−/−, Cxcl10^−/−, Ccr5^−/−, Pmel-1 Thy-1.1⁺Thy-1.1⁺, OT1 and FVB-Tg(CAG-luc) mice were bred in our mouse facility. Male Pmel-1 Thy-1.1⁺Thy-1.1⁺ mice were crossed with female Cxcr3^−/− Thy-1.2⁺Thy-1.2⁺, mice to obtain first generation males that were Pmel-1 Cxcr3^−/−Thy-1.1⁺Thy-1.2⁺. Mice used were 7-12 weeks old. For inhibition of DPP4 activity in vivo, mice were fed with chow (SAFE) formulated to contain 1.1% Sitagliptin (trade name Januvia, Merck). Sitagliptin food was administrated to mice before treatments, unless stated differently in the figure legend. Mice were maintained in a specific pathogen free facility and all experimental protocols were approved by the Cornité d'Ethique pour l'Expérimentation Animate (The ethics committee for animal experimentation) Paris.