C57bl 6antac

Manufactured by Taconic Biosciences

The C57BL/6ANTac is a strain of laboratory mouse developed and maintained by Taconic Biosciences. It is a substrain of the widely used C57BL/6 mouse model. The C57BL/6ANTac strain is a commonly used model in biomedical research.

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Lab products found in correlation

Balb canntac, by Taconic Biosciences (2 mentions) B6 cg tg k18 ace2 2prlmn j, by Jackson ImmunoResearch (1 mentions) B6 cg tg k18 ace2 2prlmn j mice, by Jackson ImmunoResearch (1 mentions)

3 protocols using c57bl 6antac

SARS-CoV-2 Mouse Model Establishment

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Five- to six-week-old female C57BL/6ANTac and B6.Cg-Tg(K18-hACE2)2Prlmn/J mice were obtained from Taconic Biosciences and Jackson Laboratories, respectively. Typically, 3–5 mice were housed per sterile, ventilated microisolator cage in an ABSL-2 or ABSL-3 facility. Female mice were used because males would have had to be caged separately to prevent aggressive behavior.

Cotter C.A., Americo J.L., Earl P.L, & Moss B. (2023). Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice. NPJ Vaccines, 8, 47.

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SARS-CoV-2 Mouse Model Establishment

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Five-to six-week-old female BALB/cAnNTac and C57BL/6ANTac were obtained from Taconic Biosciences and B6.Cg-Tg(K18-ACE2)2Prlmn/J from Jackson Laboratories. Mice were separated into groups of 2–5 animals in small, ventilated microisolator cages in an ABSL-2 facility and used after 1–5 additional 5 weeks.

Liu R., Americo J.L., Cotter C.A., Earl P.L., Erez N., Peng C, & Moss B. (2021). MVA Vector Vaccines Inhibit SARS CoV-2 Replication in Upper and Lower Respiratory Tracts of Transgenic Mice and Prevent Lethal Disease. bioRxiv.

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Murine Models of SARS-CoV-2 Infection

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The 5- to 6-wk-old female BALB/cAnNTac and C57BL/6ANTac mice were obtained from Taconic Biosciences, and B6.Cg-Tg(K18-ACE2)2Prlmn/J mice were obtained from Jackson Laboratories.

Liu R., Americo J.L., Cotter C.A., Earl P.L., Erez N., Peng C, & Moss B. (2021). One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection. Proceedings of the National Academy of Sciences of the United States of America, 118(12), e2026785118.

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