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Premier resolution system

Manufactured by Trinity Biotech
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Sourced in Ireland

The Premier Resolution system is a high-performance laboratory instrument designed for efficient and accurate analysis of biological samples. The core function of the system is to provide precise separation, detection, and quantification of various biomolecules, such as proteins, nucleic acids, and other analytes, through advanced chromatographic and spectroscopic techniques.

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Lab products found in correlation

Variant 2 system, by Bio-Rad (2 mentions) Architect i2000sr, by Abbott (2 mentions) Unicel dxh 800 automated blood cell counter, by Beckman Coulter (2 mentions)

2 protocols using premier resolution system

1

Investigating Rare Hemoglobin Variant

Check if the same lab product or an alternative is used in the 5 most similar protocols
The proband, a 31-year-old Thai man, his father, mother, wife, and son were recruited after an anomalous Hb fraction was observed in the proband during a thalassemia diagnosis program among married couples. After informed consent was obtained, peripheral blood specimens were collected and sent to the School of Allied Health Sciences, University of Phayao for further analysis of the unknown Hb variant. Hematological parameters were assessed using a UniCel DxH 800 automated blood cell counter (Beckman-Coulter Co., Miami, FL, USA), and parameters related to iron metabolism [serum iron, serum ferritin, total iron binding capacity, and transferrin saturation were determined using an automated immunoassay analyzer (ARCHITECT i2000SR, Abbott Laboratories, Abbott Park, IL, USA). Hb was analyzed using capillary electrophoresis (CE; Capillarys 2 Flex Piercing, Sebia SA, Lisses, France) and two automated cation-exchange high-performance liquid chromatography (HPLC) systems: a Premier Resolution system (Trinity Biotech, Bray, Country Wicklow, Ireland) using the high-resolution mode and the VARIANT II system (Bio-Rad Laboratories, Hercules, CA, USA) using the β-Thalassemia Short Program. The study protocol was approved by the institutional review board at the University of Phayao, Thailand (UP-HEC 1.3/020/64). Written informed consent obtained from all participants.
Panyasai S., Khongthai K, & Satthakarn S. (2023). Hemoglobin profile and molecular characteristics of the complex interaction of hemoglobin Doi-Saket [α9(A7) asn > lys, HBA2:c.30C > a], a novel α2α1 hybrid globin variant, with hemoglobin E [β26(B8) Glu > lys, HBB:c.79G > A] and deletional α+-thalassemia in a Thai family. Annals of Medicine, 55(2), 2264174.
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2

Investigating Rare Hemoglobin Variant

Check if the same lab product or an alternative is used in the 5 most similar protocols
The proband, a 31-year-old Thai man, his father, mother, wife, and son were recruited after an anomalous Hb fraction was observed in the proband during a thalassemia diagnosis program among married couples. After informed consent was obtained, peripheral blood specimens were collected and sent to the School of Allied Health Sciences, University of Phayao for further analysis of the unknown Hb variant. Hematological parameters were assessed using a UniCel DxH 800 automated blood cell counter (Beckman-Coulter Co., Miami, FL, USA), and parameters related to iron metabolism [serum iron, serum ferritin, total iron binding capacity, and transferrin saturation were determined using an automated immunoassay analyzer (ARCHITECT i2000SR, Abbott Laboratories, Abbott Park, IL, USA). Hb was analyzed using capillary electrophoresis (CE; Capillarys 2 Flex Piercing, Sebia SA, Lisses, France) and two automated cation-exchange high-performance liquid chromatography (HPLC) systems: a Premier Resolution system (Trinity Biotech, Bray, Country Wicklow, Ireland) using the high-resolution mode and the VARIANT II system (Bio-Rad Laboratories, Hercules, CA, USA) using the β-Thalassemia Short Program. The study protocol was approved by the institutional review board at the University of Phayao, Thailand (UP-HEC 1.3/020/64). Written informed consent obtained from all participants.
Panyasai S., Khongthai K, & Satthakarn S. (2023). Hemoglobin profile and molecular characteristics of the complex interaction of hemoglobin Doi-Saket [α9(A7) asn > lys, HBA2:c.30C > a], a novel α2α1 hybrid globin variant, with hemoglobin E [β26(B8) Glu > lys, HBB:c.79G > A] and deletional α+-thalassemia in a Thai family. Annals of Medicine, 55(2), 2264174.
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