Republic of China). HA (molecular weight: 3 kDa) was obtained from Shandong Freda Biopharm Co., Ltd. (Ji’nan, People's
Republic of China). Injectable soya lecithin (ISL) was obtained from Lipoid GmbH (Ludwigshafen, Germany). Compritol® 888 ATO and Glycerol Monostearate (GMS) were obtained as gifts from Gattefossé (Saint-Priest, Lyon, France). RVC hydrochloride, DMDT hydrochloride, N,N-dimethylformamide (DMF), polysorbate 80, DMEM, and MTT were purchased from Sigma Aldrich (St. Louis, MO, USA). All the other chemicals and reagents were of analytical grade or HPLC grade and used without further purification.