Image acquisition: CMR imaging was performed on a Philips Intera CV (Philips, Best, the Netherlands) with a cardiac synergy coil. All subjects were placed in supine position. Cine short-axis gradient-recalled echo images covering the left ventricle were acquired using a balanced turbo field echo (bTFE) sequence: slice thickness = 8 mm, field-of-view = 340 mm, TR = 3.14 ms, TE = 1.58 ms. In addition, three cine long-axis images (2-, 3- and 4-chamber views) were acquired using the same sequence. Approximately 15 min after intravenous administration of a commercially available extracellular gadolinium-based contrast agent (gadoteric acid, Gd-DOTA, 0.2 mmol/kg, Guerbet, Gothia Medical AB, Billdal, Sweden), an inversion-recovery (IR) sequence was used to acquire contrast-enhanced images in the corresponding planes as for the cine images. Typical IR sequence parameters were slice thickness = 8 mm, TR = 3.9 ms, TE = 1.2 ms, in-plane resolution = 1.5 x 1.5 mm, and flip angle = 15º with acquisition every heartbeat. The inversion time, typically 250-350 ms, was manually adjusted to null the signal from remote myocardium.
Intera cv
Manufactured by Philips
Sourced in Germany
The Intera CV is a laboratory equipment product from Philips. It is designed for performing cardiovascular (CV) measurements and analyses. The core function of the Intera CV is to capture and process data related to the cardiovascular system.
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Lab products found in correlation
6 protocols using intera cv
1
Cardiac MRI Imaging Protocol for Gadolinium-Enhanced Imaging
2
Cardiac MRI for Infarct Assessment
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CMR was performed on days 1 to 4 after the index event (median time interval of 61 h IQR 44–89 h) using a 1.5-T scanner (Intera CV, Philips Medical Systems, Best, The Netherlands). The well-established infarction protocol includes the assessment of left ventricular (LV) function, mass, volumes, myocardial salvage, infarct size and MO7 (link).
For area at risk determination, short-axis slices covering the whole ventricle using a T2-weighted triple inversion recovery breath-hold pulse sequence were obtained using a body coil. Late enhancement images covering the whole ventricle were acquired approximately 15 min after intravenous administration of 0.2 mmol/kg body weight of gadobutrol to assess late MO, and IS (Gadovist, Bayer Schering Pharma, Berlin, Germany). A 3-dimensional inversion recovery turbo gradient echo was used for image acquisition.
For area at risk determination, short-axis slices covering the whole ventricle using a T2-weighted triple inversion recovery breath-hold pulse sequence were obtained using a body coil. Late enhancement images covering the whole ventricle were acquired approximately 15 min after intravenous administration of 0.2 mmol/kg body weight of gadobutrol to assess late MO, and IS (Gadovist, Bayer Schering Pharma, Berlin, Germany). A 3-dimensional inversion recovery turbo gradient echo was used for image acquisition.
3
CMR Protocol for Myocardial Tissue Characterization
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A 1.5 T scanner (Intera CV, Philips Medical Systems, Best, The Netherlands) was used in all cases. Patients were monitored with single-lead ECG and pulse oximetry, and images were obtained with ECG synchronisation and apnoea. Short-axis, 2-, 3- and 4-chamber long-axis images were acquired using a standard steady-state free precision technique. LGE images were obtained 10 min after peripheral injection of 0.1 mmol/kg gadobutrol bolus (Gadovist, Bayer Schering Pharma, Berlin, Germany) using a turbo gradient echo sequence. The inversion time was determined individually to abolish the normal myocardial signal. In cases where myocardial thinning was evident on short-axis cine images, T1 fat-saturated and T1 nonfat-saturated were also acquired on that plane.
4
Cardiac MRI Image Evaluation
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A 1.5 T MRI‐scanner with a cardiac synergy coil was used (Philips Intera CV, Philips, Best, the Netherlands). All images were evaluated using freely available software (Segment 1·6‐2·0 http://segment.heiberg.se ) (Heiberg et al., 2010 ).
5
Cardiac MRI Protocol for LGE Imaging
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CMR imaging was performed on a Philips Intera CV (Best, The Netherlands) for seven patients, on a Siemens Magnetom Aera (Erlangen, Germany) for 63 patients and on a Siemens Magnetom Avanto (Erlangen, Germany) for three patients. All subjects were placed in supine position. Cine short-axis gradient-recalled echo images covering the left ventricle were acquired using a balanced turbo field echo (bTFE) sequence: slice thickness = 8 mm, field-of-view = 340 mm, TR = 3.14 ms, TE = 1.58 ms. Three cine long-axis images (2-, 3- and 4-chamber views) were acquired using the same sequence. Approximately 15 min after intravenous administration of an extracellular gadolinium-based contrast agent (gadoteric acid, Gd-DOTA, 0.2 mmol·kg−1, Guerbet, Gothia Medical AB, Billdal, Sweden) an inversion-recovery (IR) sequence was used to acquire late gadolinium enhanced (LGE) images in the corresponding planes as for the cine images. Typical LGE sequence parameters were: slice thickness = 8 mm, TR = 3.9 ms, TE = 1.2 ms, in-plane resolution = 1.5 × 1.5 mm and flip angle = 15º with acquisition every heartbeat. The inversion time, typically 250-350 ms, was manually adjusted to null the signal from remote myocardium.
6
Cardiac MRI Evaluation of LV Function
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Patients underwent CMR examination using a 1.5 T system (Magnetom Avanto or Aera, Siemens Healthineers, Erlangen, Germany; or Intera CV, Philips Healthcare, Best, The Netherlands). Standard CMR cine images were acquired using a retrospectively ECG-gated balanced steady-state free-precession (bSSFP) sequence with standard short-axis and long-axis orientations to measure LV volumes and calculate LV ejection fraction (LVEF). Typically, temporal resolution was < 50 ms and the number of reconstructed temporal phases within the cardiac cycle was set between 20 and 30. Typical image acquisition parameters were: slice thickness/slice gap: 5/5 mm, 8/0 mm or 6/4 mm; echo time (TE)/repetition time (TR): 1.6 ms/3.2 ms; in-plane spatial resolution: 1.5 by 2.1 mm; flip angle: 45 to 75 degrees. Cine imaging of the LV in the three-chamber view was performed to assess aortic valve closure (AVC). Myocardial scar territory was assessed by late gadolinium enhancement (LGE) imaging, and infarct size was measured using the full width at half maximum method [12 (link)]. All CMR data were analyzed using dedicated offline software (QMassMR version 7.6, Medis, Leiden, The Netherlands).
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