Isonicotinic acid hydrazide

Manufactured by Merck Group

Sourced in United States

Isonicotinic Acid Hydrazide is a chemical compound used as a laboratory reagent. It is a white crystalline solid with the molecular formula C₆H₇N₃O. The compound is used in various applications, including chemical synthesis and research, but a detailed description of its core function is not available while maintaining an unbiased and factual approach.

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Lab products found in correlation

Ethambutol dihydrochloride, by Merck Group (1 mentions) Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Rifampicin, by Merck Group (1 mentions) Ferrous chloride tetrahydrate, by Merck Group (1 mentions) Ferric chloride hexahydrate, by Merck Group (1 mentions) Pyrazinamide, by Merck Group (1 mentions) 4 amino salicylic acid, by Merck Group (1 mentions) Sodium amp salt, by Merck Group (1 mentions) Chitosan, by Merck Group (1 mentions) Sodium hydroxide (naoh), by Merck Group (1 mentions)

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Isonicotinic acid (9 citations)

2 protocols using isonicotinic acid hydrazide

Antimycobacterial Compound Preparation

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The compounds Isonicotinic Acid Hydrazide (Isoniazid, INH), Rifampicin (RIF), Ethambutol Dihydrochloride (ETB), Pyrazinoic Acid Amide (Pyrazinamide, PZA) were purchased from Sigma. All compounds, except Pyrazinamide, which was made up in media, were made up in DMSO (Sigma). Final DMSO concentration was adjusted and used at 0.1% in all test conditions.

Aljayyoussi G., Jenkins V.A., Sharma R., Ardrey A., Donnellan S., Ward S.A, & Biagini G.A. (2017). Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration. Scientific Reports, 7, 502.

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Synthesis and Characterization of Chitosan-Based Composites

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The chemicals in this study were reagent grade and were used as received without purification. Ferrous chloride tetrahydrate (FeCl₂·4H₂O), ferric chloride hexahydrate (FeCl₃·6H₂O), and sodium hydroxide (NaOH) were purchased from Merck KGaA (Darmstadt, Germany). Chitosan, deacetylated at 75%–85%, sodium amp salt (>98% purity; molecular weight 371.4 g/mol), 4-amino salicylic acid, isonicotinic acid hydrazide, and pyrazinamide were purchased from Sigma-Aldrich Co. (St Louis, MO, USA). Acetic acid (99.8%) was purchased from Hamburg Industries (Hamburg, Germany). Deionized water was used in each experiment.

Hussein-Al-Ali S.H., El Zowalaty M.E., Hussein M.Z., Geilich B.M, & Webster T.J. (2014). Synthesis, characterization, and antimicrobial activity of an ampicillin-conjugated magnetic nanoantibiotic for medical applications. International Journal of Nanomedicine, 9, 3801-3814.

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