Alphanate
Alphanate is a plasma-derived factor VIII concentrate. It is used to treat and prevent bleeding episodes in patients with hemophilia A.
Lab products found in correlation
3 protocols using alphanate
Platelet Aggregation Assay Protocol
FVIII and VWF Inhibitor Interactions
Inhibitor human IgG was purified from a commercial pool of haemophilic plasmas with inhibitors (Technoclone, Vienna, Austria) using protein G Sepharose chromatography (GE Healthcare, Uppsala, Sweden). Characterization of the pool performed in our laboratory showed the presence of antibodies against both light and heavy (A1–A2) chains. The Mab ESH-8, human anti-FVIII C2 domain antibody was obtained from American Diagnostica GbmH (Pfungstadt, Germany).
Expression and Purification of Recombinant VWF Variants
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