During infancy, children received either a diphtheria, tetanus, wP, inactivated polio virus, Haemophilus influenzae type b (DTwP-IPV-Hib; Netherlands Vaccine Institute, Bilthoven, the Netherlands) (wP-primed children), or a DTaP-IPV-Hib [Infanrix-IPV-Hib™, GlaxoSmithKline (GSK), Rixensart, Belgium] (aP-primed children) combination vaccine at 2, 3, 4, and 11 months of age. Children received a pediatric DTaP booster vaccination at 4 years of age [Infanrix-IPV™, GSK; containing 25 µg pertussis toxin (PT) and filamentous hemagglutinin (FHA), 8 µg pertactin (Prn), ≥30 IU diphtheria toxoid (Dd), and ≥40 IU tetanus toxoid (Td)]. In addition, a Tdap booster vaccination was administered to children 9 years of age (Boostrix-IPV™, GSK; containing 8 µg PT and FHA, 2.5 µg Prn, ≥2 IU Dd, and ≥20 IU Td).
Infanrix ipv
Manufactured by GlaxoSmithKline
Sourced in Belgium
Infanrix-IPV is a vaccine developed by GlaxoSmithKline. It is designed to protect against diphtheria, tetanus, pertussis (whooping cough), and polio. The vaccine is administered by intramuscular injection.
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Lab products found in correlation
3 protocols using infanrix ipv
1
Childhood Vaccination Schedule Evaluation
2
Infanrix-IPV Vaccine Composition and Administration
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Infanrix-IPV, manufactured by GSK, Belgium, comes in a sterile suspension in a single-dose prefilled syringe. Each 0.5 mL vaccine dose contains antigens against the four target pathogens; a minimum of 30 international units (IU) of diphtheria toxoid, 40 IU of tetanus toxoid, three purified antigens of Bordetella pertussis (25 μg of pertussis toxoid [PT], 25 μg of filamentous haemagglutinin [FHA] and 8 μg of pertactin [PRN], each adsorbed onto aluminium salt), and three distinct poliovirus antigens; 40 D-antigen units of type 1 poliovirus (Mahoney strain), 8 D-antigen units of type 2 poliovirus (MEF-1 strain) and 32 D-antigen units of type 3 poliovirus (Saukett strain). The vaccine is administered intramuscularly in the thigh (infants ≤2 years) or deltoid (in older children).
3
4-Year-Old Routine Immunizations Study
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Parents/guardians of children attending the clinic for their routine 4-year-old immunisations will be approached to participate in the study. In Australia, the recommended 4-year-old immunisations are included in a single combination injection, which includes diphtheria, tetanus, pertussis and poliomyelitis. In Victoria, the available vaccine brands are Infanrix IPV (GlaxoSmithKline) or Quadracel (Sanofi Pasteur Inc).6
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