Pluronic f68 poloxamer 188 f68

Manufactured by Merck Group

Sourced in Germany

Pluronic F68 (poloxamer 188 (F68)) is a non-ionic block copolymer surfactant. It is a triblock copolymer composed of a central hydrophobic chain of polypropylene oxide (PPO) flanked by two hydrophilic chains of polyethylene oxide (PEO). Pluronic F68 is primarily used as a wetting agent, emulsifier, and stabilizer in various laboratory and industrial applications.

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Lab products found in correlation

Hplc grade acetonitrile, by Merck Group (1 mentions) Ethanol, by Merck Group (1 mentions) Polyvinyl alcohol (pva), by Merck Group (1 mentions) Mannitol, by Merck Group (1 mentions) Trehalose, by Merck Group (1 mentions)

Spelling variants of this product

Pluronic F68 (196 citations) Poloxamer 188 (114 citations) Poloxamer 188 (F68), (2 citations) Pluronic 188 (2 citations)

2 protocols using pluronic f68 poloxamer 188 f68

Formulation and Characterization of Efavirenz Nanoparticles

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The raw efavirenz (EZ) was obtained from Shanghai Desano Chemical Pharmaceutical Co., Ltd. (China). Polyvinyl alcohol (PVA) with an average molecular weight of 30000 - 70000 and Pluronic F68 (poloxamer 188 (F68)) were supplied from Sigma-Aldrich (Germany). Sodium carboxymethylcellulose (CMC) was from ICN Biomedicals (USA). Hydroxypropyl methylcellulose (HPMC E5), mannitol, sodium lauryl sulfate (SLS), methanol, ethanol, and acetonitrile (HPLC grade) were purchased from Merck (Germany).

Rashed M., Dadashzadeh S, & Bolourchian N. (2022). The Impact of Process and Formulation Parameters on the Fabrication of Efavirenz Nanosuspension to Improve Drug Solubility and Dissolution. Iranian Journal of Pharmaceutical Research : IJPR, 21(1), e129409.

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Formulation and Evaluation of Carvedilol Nanoparticles

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Carvedilol (CA) (Damavand Darou Co, Iran), pluronic F68 (poloxamer 188 (F68)), trehalose, and myrj 52 [polyoxyethylene (40) stearate] (Sigma-Aldrich, Germany), and mannitol (Merck, Germany) were purchased and used in this study. All other solvents and chemicals used in the study were of pharmaceutical grades.

Bolourchian N, & Shafiee Panah M. (2022). The Effect of Surfactant Type and Concentration on Physicochemical Properties of Carvedilol Solid Dispersions Prepared by Wet Milling Method. Iranian Journal of Pharmaceutical Research : IJPR, 21(1), e126913.

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