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1 2 dilauroyl sn glycero 3 phosphatidylcholine

Manufactured by Avanti Polar Lipids
Sourced in United States

1,2-dilauroyl-sn-glycero-3-phosphatidylcholine is a synthetic phospholipid compound used in various laboratory applications. It is a zwitterionic lipid with a choline headgroup and two lauric acid acyl chains. This compound is commonly used as a model system for studying membrane biophysics and as a component in liposome formulations.

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2 protocols using 1 2 dilauroyl sn glycero 3 phosphatidylcholine

1

Lipid Standards Characterization

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The lipids 1,2-dilauroyl-sn-glycero-3-phosphatidylcholine (DLPC), 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphatidylglycerol (DMPG), 1-myristoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine (lyso-MPC), 1-myristoyl-2-hydroxy-sn-glycero-3-phosphatidylglycerol (lyso-MPG), and 1-lauroyl-2-hydroxy-sn-glycero-3-phosphatidylcholine (lyso-LPC) were purchased from Avanti Polar Lipids (Alabaster, AL, USA).
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2

Deuterium-Labeled Peptide Synthesis

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Peptide synthesis reagents and Fmoc-protected amino acids were purchased from Merck Biosciences (Darmstadt, Germany) and Iris Biotech (Marktredwitz, Germany). 2 H-labelled 2,2,2-2 H 3 -L-Ala (Ala-d 3 ) was purchased from Cambridge Isotope Laboratories (Andover, MA, USA), and its N-terminus was Fmoc-protected. 32 Solvents were purchased from Merck (Darmstadt, Germany). The lipids 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC), 1-myristoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine (lyso-MPC), 1,2dimyristoleoyl-sn-glycero-3-phosphatidylcholine (DMoPC), 1,2-dimyristoleoyl-sn-glycero-3phosphatidylglycerol (DMoPG) 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC), and 1,2-dilauroyl-sn-glycero-3-phosphatidylcholine (DLPC) were obtained from Avanti Polar Lipids (Alabaster, AL, USA).
Table 1. Synthesized peptides used in the 2 H-NMR analysis. The highlighted Ala-d 3 was labeled with deuterium at the side chain methyl-group.
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