Phenylephrine HCl, Acetylcholine chloride, Prazosin HCl, and Sodium nitroprusside dihydrate were all obtained from Sigma Chemical Company (St. Louis, MO, USA). Sildenafil was bought from the government pharmaceutical organization (GPO) of Thailand (Bangkok, Thailand). DMSO was acquired from VWR International Ltd. (Prolabo Chemicals, UK). All quinazoline analogues were dissolved in DMSO (100%) and diluted with distilled water.
Prazosin hcl
Manufactured by Merck Group
Sourced in United States, Australia
Prazosin HCl is a laboratory reagent produced by Merck Group. It is a hydrochloride salt of the alpha-1 adrenergic receptor antagonist, Prazosin. Prazosin HCl is commonly used in scientific research applications for its pharmacological properties.
Automatically generated - may contain errors
Lab products found in correlation
Dimethyl sulfoxide (dmso), by Avantor (1 mentions)
Sodium nitroprusside dihydrate, by Merck Group (1 mentions)
Acetylcholine chloride, by Merck Group (1 mentions)
Phenylephrine hcl, by Merck Group (1 mentions)
Bk acetate, by Merck Group (1 mentions)
Genistein, by Merck Group (1 mentions)
Tempol, by Merck Group (1 mentions)
Carbachol, by Merck Group (1 mentions)
Apocynin, by Merck Group (1 mentions)
Pd123319, by Merck Group (1 mentions)
L phenylephrine hcl, by Merck Group (1 mentions)
Nnc 55 0396, by Bio-Techne (1 mentions)
Idazoxan hcl, by Merck Group (1 mentions)
Nifedipine, by Merck Group (1 mentions)
Losartan, by Merck Group (1 mentions)
Skf96365, by Bio-Techne (1 mentions)
Nf449, by Bio-Techne (1 mentions)
3 protocols using prazosin hcl
1
Vasoactive Compounds: Preparation and Testing
2
Preparation and Application of Receptor Agonists
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were prepared as stock solution in dH2O, freshly on the day of experiment respectively, 40 mM prazosin–HCl (Sigma-Aldrich), 20 mM NE bitartrate (Sigma-Aldrich) and 20 mM BK acetate (Sigma-Aldrich). Stocks were diluted again 1:10 or 1:100 and as a bolus directly applied to the bath solution during the recordings.
3
Pharmacological Modulation of Vascular Function
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Ang II was from Auspep (Tullamarine, VIC, Australia). L-phenylephrine HCl, carbachol (carbamoylcholine chloride), prazosin HCl, idazoxan HCl, nifedipine, losartan, PD 123319, genistein, tempol and apocynin were from Sigma-Aldrich Chemical Company (Castle Hill, NSW, Australia). SKF 96365, efonidipine HCl, NNC 55-0396, UK 14,304 tartrate, and NF449 were from Tocris Bioscience (Bristol, UK). Tetrodotoxin was from Alamone (Jerusalem, Israel). Efonidipine was prepared as a 10 mM stock solution in dimethylsulphoxide (DMSO; final working concentration of DMSO 0.01% (v/v)). Prazosin was prepared as a 1 mM stock solution in 10% (v/v) DMSO in water. nifedipine was prepared as 10 mM stock solutions in ethanol and apocynin was prepared on the day of the experiment at 300 mM in ethanol (final working concentration of ethanol 0.1% (v/v)). All other drugs were made up as 1 mM stock solutions in water.
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