Mazindol

Manufactured by Lipomed

Sourced in Switzerland

Mazindol is a laboratory equipment product manufactured by Lipomed. It is a chemical compound used in research and analytical applications. The core function of Mazindol is to serve as a reference standard or analytical tool, but no further details on its intended use can be provided in an unbiased and factual manner.

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Lab products found in correlation

2 protocols using mazindol

Radioligand Binding Assay Protocol

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Buprenorphine, citalopram, codeine, dextromethorphan, dihydrocodeine, fentanyl, heroin (diacetylmorphine, diamorphine), 6‐acetylmorphine (6‐mono‐acetylmorphine), hydrocodone, hydromorphone, mazindol, MDMA, methadone, morphine, oxycodone, oxymorphone, pethidine (meperidine), tramadol, O‐desmethyl‐cis‐tramadol, tapentadol, venlafaxine and fluoxetine were purchased from Lipomed (Arlesheim, Switzerland). Mianserin, nisoxetine, pargyline, pindolol and spiperone were supplied by Sigma‐Aldrich (Buchs, Switzerland). D(S)‐methadone and l(R)‐methadone were obtained from Alsachim (Illkirch Graffenstaden, France). The HPLC purity of all of the substances was >98%. [³H]‐8‐OH‐DPAT, [³H]‐ketanserin and [³H]‐mesulergine were supplied by Perkin‐Elmer.

Rickli A., Liakoni E., Hoener M.C, & Liechti M.E. (2018). Opioid‐induced inhibition of the human 5‐HT and noradrenaline transporters in vitro: link to clinical reports of serotonin syndrome. British Journal of Pharmacology, 175(3), 532-543.

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Pharmacological Characterization of Novel Synthetic Cathinones and Amphetamines

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Mazindol, MDA HCl, MDMA HCl, MDPV HCl, methylone HCl, and fluoxetine HCl were purchased from Lipomed (Arlesheim, Switzerland). Nisoxetine HCl was obtained from Sigma Aldrich (Buchs, Switzerland). 3,4-Dihydroxyamphetamine (HHA) HCl, 3,4-dihydroxymethamphetamine (HHMA) fumarate, 4-hydroxy-3-methyoxyamphetamine (HMA) fumarate, and 4-hydroxy-3-methoxymethamphetamine (HMMA) HCl were synthesized and analysed for purity at the Research Triangle Institute (RTI, Durham, NC, USA) (Schindler et al., 2014 (link)). 3,4-Dihydroxymethcathinone (HHMC) HBr, 4-hydroxy-3-methyoxymethcathinone (HMMC) HCl, and 3,4-methylenedioxycathinone (MDC) HCl, were synthesized as described in (Ellefsen et al., 2015 ); 3,4-dihydroxypyrovalerone (HHPV) HBr and 4-hydroxy-3-methyoxypyrovalerone (HMPV) HCl were synthesized as described in (Anizan et al., 2014 (link)). All drugs were used as racemic mixtures. Radiolabeled [³H]norepinephrine (13.1 Ci/mmol) and [³H]dopamine (30.0 Ci/mmol) were attained from Perkin-Elmer (Schwerzenbach, Switzerland). Radiolabeled [³H]5-HT (80 Ci/mmol) was obtained from Anawa (Zurich, Switzerland).

Luethi D., Kolaczynska K.E., Walter M., Suzuki M., Rice K.C., Blough B.E., Hoener M.C., Baumann M.H, & Liechti M.E. (2019). Metabolites of the ring-substituted stimulants MDMA, methylone, and MDPV differentially affect human monoaminergic systems. Journal of psychopharmacology (Oxford, England), 33(7), 831-841.

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