4 6 diaminidino 2 pheylindole dapi

Rink-amide resin, protected amino acids, and solvents used for peptide synthesis were obtained from Protein Technologies Inc. (Tucson, AZ). Fluorescein isothiocyanate (FITC), trifluoroacetic acid, thioanisole, anisole, 1,2-ethanedithiole, methyl-tert-butyl ether, N,N-diisopropylethylamine, hydrazine, GSH, MA, and 3MA were purchased from Sigma-Aldrich (Saint-Louis, MO). Sulfosuccinimidyl 4-[N-maleimidomethyl]cyclohexane-1-carboxylate (sulfo-SMCC) was obtained from Novachem (Calgary, Canada) and p-SNC-deferoxamine (DFO) was from Macrocyclics Inc. (Plato, TX). AlDoxorubicin was purchased from Medkoo Biosciences (Chapel Hill, NC). Doxorubicin was from LC Laboratories (Woburn, MA), and N2′- deacetyl-N2′-(3-mercapto-1-oxopropyl)-maytansine was supplied by Carbosynth Ltd (Compton, WB). Uranyl formate was purchased from Electron Microscopy Sciences (Hatfield, PA), and 4′6-diaminidino-2-pheylindole (DAPI) and LysoTracker Red were purchased from Life Technologies Inc. (Norwalk, CT). Cyanine5.5 NHS ester was obtained from Lumiprobe Corporation (Hallandale Beach, FL) and luciferin was supplied by Caliper LifeSciences (Hopkinton, MA).

All of the protected amino acids, resins, and solvents for peptide synthesis were purchased from Protein Technologies Inc. (Tucson, AZ). Trifluoroacetic acid (TFA), thioanisole, anisole, methyl-tert-butyl ether, N,N-diisopropylethylamine (DIPEA), and hydrazine were obtained from Sigma-Aldrich (St. Louis, MO). N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-maytansine (DM1) was supplied by Carbosynth Ltd. (Compton, WB). CathB (purified from bovine spleen) and its inhibitor II were obtained from EMD Millipore (Billerica, MA). Uranyl formate was purchased from Electron Microscopy Sciences (Hatfield, PA). Sulfosuccinimidyl 4-[N-maleimidomethyl]cyclohexane-1-carboxylate (sulfo-SMCC), 4′6-dia-minidino-2-pheylindole (DAPI), and LysoTracker Red were obtained from Life Technologies Inc. (Norwalk, CT).