3 4 dihydroxy dl phenylalanine dopa

Manufactured by Merck Group

Sourced in Italy

3,4-dihydroxy-DL-phenylalanine (DOPA) is a chemical compound commonly used in laboratory experiments. It is a mixture of two stereoisomers, D-DOPA and L-DOPA, which are the enantiomers of the amino acid 3,4-dihydroxyphenylalanine. DOPA serves as a precursor for the synthesis of various neurotransmitters and hormones in biological systems.

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Lab products found in correlation

Dichloromethane, by Merck Group (1 mentions) Chloroform, by Merck Group (1 mentions) Formic acid, by Merck Group (1 mentions) Polycaprolactone, by Polysciences (1 mentions) Human collagen type 1, by Corning (1 mentions) Human fibronectin, by Merck Group (1 mentions)

Spelling variants of this product

Phenylalanine (126 citations) DL-phenylalanine (9 citations) DL-DOPA (8 citations) 3,4-dihydroxy-dl-phenylalanine (2 citations)

3 protocols using 3 4 dihydroxy dl phenylalanine dopa

Biopolymeric Microparticle Fabrication

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Poly(lactic-co-glycol) acid (LA:GA 75:25, Mw = 66–107 kDa, PLGA), 3,4-dihydroxy-DL-phenylalanine (DOPA) and type A gelatin from porcine skin (G) were purchased from Sigma-Aldrich (Milan, Italy). 2-Amino-2-(hydroxymethyl)-1,3-propanediol (TRIS), hydrochloric acid (HCl), and dichloromethane were purchased from Sigma-Aldrich (Milan, Italy).
All solvents were of analytical grade and used without further purification and supplied from Sigma-Aldrich.

Carmagnola I., Chiono V., Ruocco G., Scalzone A., Gentile P., Taddei P, & Ciardelli G. (2020). PLGA Membranes Functionalized with Gelatin through Biomimetic Mussel-Inspired Strategy. Nanomaterials, 10(11), 2184.

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Polycaprolactone-Based Biomaterial Synthesis

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Polycaprolactone (M_w = 43,000 Da, PCL) was supplied by Polysciences; chloroform 99.8% and formic acid 98% were purchased from Sigma-Aldrich (Milan) and were used without further purification. 3,4-Dihydroxy-DL-phenylalanine (DOPA) and porcine gelatin (G) type A were obtained from Sigma-Aldrich (Milan).

Spedicati M., Ruocco G., Zoso A., Mortati L., Lapini A., Delledonne A., Divieto C., Romano V., Castaldo C., Di Meglio F., Nurzynska D., Carmagnola I, & Chiono V. (2022). Biomimetic design of bioartificial scaffolds for the in vitro modelling of human cardiac fibrosis. Frontiers in Bioengineering and Biotechnology, 10, 983872.

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Biofunctionalized PCL Scaffold Synthesis

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PCL with a weight-average
molecular weight of 43,000 g mol^–1 was purchased
from Polysciences. 3,4-Dihydroxy-dl-phenylalanine (DOPA)
and human fibronectin were supplied from Sigma-Aldrich, Milano. Human
collagen type I was supplied from Corning. All the other reagents
were purchased from Sigma-Aldrich.

Ruocco G., Zoso A., Mortati L., Carmagnola I, & Chiono V. (2023). Biomimetic Electrospun Scaffold-Based In Vitro Model Resembling the Hallmarks of Human Myocardial Fibrotic Tissue. ACS Biomaterials Science & Engineering, 9(7), 4368-4380.

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