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3387 lead

Manufactured by Medtronic
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The 3387 lead is a medical device component designed for use in implantable cardiac devices. It serves as an electrical connection between the device and the patient's heart. The core function of the 3387 lead is to transmit electrical signals between the device and the heart tissue. Detailed specifications and intended use would require further information.

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Model 3387 DBS Lead (3 citations)

3 protocols using 3387 lead

1

Evaluating Lead Design Robustness

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Several steps were taken to generate a performance metric that could be used to evaluate the overall robustness of each lead design. The steps to evaluate one lead design are summarized below and each step is explained in greater detail throughout the methods sections.
Figure 2 demonstrates how each step contributes to an overall robustness evaluation by averaging the performance metric across all tested lead locations for a single Medtronic 3387 lead. The figure illustrates both the percent fiber activation and resultant performance variation calculation as the lead moves over a range of representative positions. The violin plot for the 3387 lead illustrates that although the normalized performance metric has both a median and mean in the middle of the range, most of the data values are skewed toward the maximum and minimum of the scale which is not evident from a box plot alone.
Janson A.P., Anderson D.N, & Butson C.R. (2020). Activation robustness with directional leads and multi-lead configurations in deep brain stimulation. Journal of neural engineering, 17(2), 026012.
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2

Evaluating Lead Design Robustness

Check if the same lab product or an alternative is used in the 5 most similar protocols
Several steps were taken to generate a performance metric that could be used to evaluate the overall robustness of each lead design. The steps to evaluate one lead design are summarized below and each step is explained in greater detail throughout the methods sections.
Figure 2 demonstrates how each step contributes to an overall robustness evaluation by averaging the performance metric across all tested lead locations for a single Medtronic 3387 lead. The figure illustrates both the percent fiber activation and resultant performance variation calculation as the lead moves over a range of representative positions. The violin plot for the 3387 lead illustrates that although the normalized performance metric has both a median and mean in the middle of the range, most of the data values are skewed toward the maximum and minimum of the scale which is not evident from a box plot alone.
Janson A.P., Anderson D.N, & Butson C.R. (2020). Activation robustness with directional leads and multi-lead configurations in deep brain stimulation. Journal of neural engineering, 17(2), 026012.
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3

Pulse Width and Directional Neurostimulation Selectivity

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We first tested the effects of pulse width tuning on neural selectivity. We found the maximum distances for which 2.0 and 5.7 μm axons are activated by 60 μs, −1.0 V pulses from the Medtronic 3387 lead. Maintaining 2.0 and 5.7 μm axons at these distances, we found activation thresholds for both axons with pulse widths from 20 to 450 μs to determine the effect of pulse width on selectivity. To test the effects of directional stimulation on neural selectivity, we found the maximum distances for which 2.0 and 5.7 μm fibers are activated by 60 μs, −1.0 mA pulses from the Abbott 6173 lead with two active contacts. Maintaining 2.0 and 5.7 μm axons at these distances, we found activation thresholds for both axons during ring mode and single contact directional simulation to determine the effect of segmented contacts on selectivity.
Anderson C.J., Anderson D.N., Pulst S.M., Butson C.R, & Dorval A.D. (2020). Neural Selectivity, Efficiency, and Dose Equivalence in Deep Brain Stimulation through Pulse Width Tuning and Segmented Electrodes. Brain stimulation, 13(4), 1040-1050.
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