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2 hydroxypropyl β cyclodextrin hp β cd

Manufactured by Cyclolab
Sourced in Hungary

2–Hydroxypropyl–β–cyclodextrin (HP–β–CD) is a modified form of the naturally occurring cyclodextrin compound. It is a cyclic oligosaccharide consisting of seven glucose units. The hydroxypropyl group is introduced to improve the water solubility and complexation properties of the cyclodextrin.

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2 protocols using 2 hydroxypropyl β cyclodextrin hp β cd

1

Cyclodextrin-Mediated Antioxidant Evaluation

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All chemicals were of the highest purity available and used as received. Gallic acid monohydrate (98.0% pure) and gallates (propyl gallate, PG, butyl gallate, BG, octyl gallate, OG, and lauryl gallate, LG, all 99.0% pure) were purchased from Sigma–Aldrich. 2–Hydroxypropyl–β–cyclodextrin (HP–β–CD) and methyl–β–cyclodextrin (M–β–CD) were purchased form Cyclolab LTD and acetonitrile was received from (ACN, HLPC grade) Merck. The Folin-Ciocalteu’s reagent was obtained by VWR Chemical. Sodium carbonate and 2,2–diphenyl–1–pycrilhydrazyl (DPPH) were purchased from Sigma–Aldrich. Milli-Q grade water (conductivity < 0.1 mS cm−1) was employed in the preparation of aqueous solutions. Citric acid and sodium citrate (both from Acros Organics, 99% pure) 0.04 M, pH 3.65, was used as buffer solution.
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2

Cyclodextrin-based Topical Formulation

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MEL-P was obtained from Egis Ltd. (Budapest, Hungary). (2-Hydroxy)-propyl-β-cyclodextrin (HPβCD) and α-cyclodextrin (αCD) were from Cyclolab Ltd. (Budapest, Hungary). Hyaluronic acid (sodium salt) (HA) was from Contipro Biotech (Dolní Dobrouč, Czech Republic), poly(vinylalcohol) (PVA) and mucin (from porcine stomach, type II) were from Sigma-Aldrich (Sigma-Aldrich Co. LLC, St. Louis, MO, USA).
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