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Advance whole body scanner

Manufactured by GE Healthcare

The Advance whole body scanner is a medical imaging device designed for comprehensive scanning of the human body. It utilizes advanced imaging technology to capture detailed images of the body's internal structures. The core function of this equipment is to provide healthcare professionals with high-quality diagnostic information to support patient care and treatment.

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2 protocols using advance whole body scanner

1

Multimodal PET Imaging of Cerebral Physiology

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PET scans were performed for each subject using an advance whole body scanner (General Electric Medical Systems, Milwaukee, WI).21 (link) First, a series of 15O-gas studies was performed.21 (link) C15O2 and 15O2 were continuously delivered via a mask throughout the 5-minute scan. Cerebral blood volume was measured by bolus inhalation of C15O and scanning for 3 minutes. The 15O-gas study was followed by a study of 11C-FMZ.22 (link) After intravenous injection of 11C-FMZ, a 50-minute dynamic PET scan was initiated simultaneously with tracer administration.
The steady-state method was used to calculate CBF, cerebral metabolic rate of oxygen (CMRO2), and oxygen extraction fraction.23 (link),24 (link) Dynamic data and Logan graphical analysis with reference tissue was used to calculate the binding potential (nondisplaceable) of 11C-FMZ, using the time-activity curves obtained from the pons.22 (link),25 (link)
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2

PET Imaging of Cerebral Metabolism and Benzodiazepine Receptor Binding

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PET scans were performed in each subject using an Advance wholebody scanner (General Electric Medical Systems, Wauwatosa, WI), which permits the simultaneous acquisition of 35 image slices with an interslice spacing of 4.25 mm. 18 (link) After a transmission scan using 68 Ge / 68 Ga, a series of 15 (link) O-gas studies was performed. 18 (link) Briefly, C 15 (link) The 15 O-gas study was followed by a study of 11 C-FMZ, 6,7,19 which was synthesized by 11 (link) C-methylation of demethylated-FMZ (Hoffmann-La Roche, Basel, Switzerland). After the slow intravenous injection of 11 C-FMZ, a 50-minute dynamic PET scan was initiated.
We used the steady-state method to calculate cerebral blood flow (CBF), cerebral metabolic rate of oxygen (CMRO 2 ), and OEF. 20 The CMRO 2 and OEF were corrected on the basis of CBV. The binding potential (BP [nondisplaceable]) of 11 C-FMZ was calculated using dynamic data and Logan graphical analysis with reference tissue, with the pons as the reference region. 19, 21 (link)
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