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Norfentanyl

Manufactured by Merck Group
Sourced in Canada

Norfentanyl is a chemical compound that is used as a laboratory standard and reference material. It is a metabolite of the opioid analgesic fentanyl. Norfentanyl is commonly used in analytical and forensic applications for the identification and quantification of fentanyl and related compounds.

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2 protocols using norfentanyl

1

Comprehensive Fentanyl Analogue Analysis

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Reagents and standards of furanylFentanyl, 4-fluorobutyrFentanyl, acrylFentanyl, butyrylFentanyl, and 4-anilino-N-phenethyl-piperidine (4-ANPP) were produced by Chiron (Trondheim, Norway). AcetylFentanyl and carfentanil were obtained by Toronto Research Chemicals (North York, Canada) while ocfentanil and norFentanyl were purchased from Sigma-Aldrich (Milan, Italy). CyclopropylFentanyl, α-methylFentanyl, and β-hydroxyFentanyl were provided by National Institute of Health (ISS). Fentanyl and the deuterated internal standards (norFentanyl-d5, Fentanyl-d5) were produced by Cerilliant (Round Rock, Texas, USA). All other chemicals were purchased from Sigma-Aldrich (Milan, Italy). Ultra-pure water was obtained using a Milli-Q® UF-Plus apparatus (Millipore, Bedford, MA, USA). All stock standard solutions were prepared in methanol at 1 mg/mL and stored at − 20 °C until used. Working solutions were prepared at the final concentration of 1000 ng/mL by dilution with methanol.
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2

Graphene Oxide and Illicit Drug Analysis

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Aqueous solutions of phosphate-buffered
saline
(PBS) (1.8 mM KH2PO4, 10 mM Na2HPO4, 2.7 mM KCl, and 137 mM NaCl all from Fisher Scientific)
pH 7.4 were prepared with Millipore Milli-Q ultrapure water (18.2
MΩ cm). The GO suspension (Graphenea, particle size < 10
μm) was diluted from 4 mg/mL to a final concentration of 1 mg/mL
with PBS. Fentanyl, norFentanyl, alfentanil, carfentanil, lorazepam,
heroin, and cocaine were all sourced as analytical standards (1 or
0.1 mg/mL in methanol or acetonitrile) from Sigma-Aldrich (Cerilliant),
and caffeine and sucrose (from Sigma-Aldrich) were diluted to the
required final concentration with PBS (structures are shown in Figure 1).
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