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3 protocols using pentaerythritol tetra 3 mercaptopropionate petmp

1

Polymer Synthesis Using Photoinitiators

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Divinyl adipate (DVA) was purchased from TCI Chemicals (Eschborn, Germany). Pentaerythritol tetra-3-mercaptopropionate (PETMP), propyl gallate and bis(2,4,6-trimethylbenzoyl) phenylphosphine oxide (BAPO) were obtained from Sigma-Aldrich (St. Louis, MO, USA). All chemicals were used as received.
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2

Thiol-ene Resin Synthesis and Curing

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2,2-bis [4-(2-hydroxy-3-methacryloyloxypropoxy)phenyl]propane (Bis-GMA), triethylene glycol dimethacrylate (TEGDMA), and Pentaerythritol tetra(3-mercaptopropionate) (PETMP) were purchased from Sigma-Aldrich (Shanghai) Trading Co., Ltd. Shanghai, China. Dicyclohexylmethane 4,4′-diisocyanate (HMDI), Phloroglucinol (TPX) were obtained from Beijing InnoChem Science & Technology Co., Ltd. Beijing, China. 1,3,5-Triallyl-1,3,5-Triazine-2,4,6(1H,3H,5H)-Trione (TTT), Camphorquinone (CQ), Triethylamine (Et3N) and 2-(Dimethylamino)ethyl methacrylate (DMAEMA) were purchased from Shanghai Titan Scientific Co., Ltd. Shanghai, China. All chemicals were used without further purification.
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3

Synthesis and Characterization of Functional Polymers

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All solvents and reagents were of analytical or HPLC grade and purchased from Sigma Aldrich (UK) or Fisher Scientific (UK) unless otherwise stated. Deuterated solvents were from Sigma Aldrich (UK) or Cambridge Isotopes (UK). Monomers used in this study (Polyethylene glycol methyl ether (PEGMA-ME 188, Mn 188), polyethylene glycol ethyl ether (PEGMA-EE 246, Mn 246), and polyethylene glycol methyl ether (PEGMA-ME475, Mn 475) were purchased from Sigma Aldrich (UK) and purified before use by passing through a column filled with neutral alumina. 2,2-azobisisobutyronitrile (AIBN) was purchased from Sigma Aldrich (UK) then recrystallized from methanol. Pentaerythritol Tetra (3-mercaptopropionate) (PETMP) and 2butanone were used as received from Sigma Aldrich (UK). Risedronate sodium was kindly supplied by SPIC Pharma (India). Spectra/Por dialysis membrane, 12,000-14,000 molecular weight cutoff, was purchased from Spectrum Laboratories (Canada). MTT (3-(4,5dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide), HEPES buffer, gentamycin, dimethylsulfoxide and sodium lauryl sulphate (SLS) from Sigma-Aldrich (UK). Foetal calf serum, Minimum Essential Medium (MEM), from Lonza (Belgium); and L-glutamine GIBCO ® , were purchased from Thermo Fisher Scientific (USA).
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