Ingenuity pathway analysis software ipa trial version

The modulated proteins identified in nanoLC-MS/MS were classified according to their Gene Ontology descriptions using information from the GO database and PANTHER (http://www.pantherdb.org/) classification systems. The predicted protein-protein interaction networks and canonical pathways were generated by Ingenuity Pathway Analysis Software (IPA trial version, Ingenuity Systems, www.ingenuity.com) (Qiagen, USA) using inputs of gene identifiers, log2 fold-changes and p-values between two-group comparisons.

To understand pathways modulated by sanguinarine, a list of differentially expressed (> 1.8 fold) was compiled. These proteins were categorized according to their Gene ontology (GO) descriptions using information from the GO database and PANTHER (Protein ANnalysis THrough Evolutionary Relationships; http://www.pantherdb.org/) classification systems. The proteins were projected on the basis of their molecular functions, biological processes and protein classes.
The canonical pathways, disease/function pathways and protein-protein interactions were analyzed using Ingenuity Pathway Analysis Software (IPA trial version, Ingenuity Systems, http://www.ingenuity.com) (Qiagen) [36 (link)]. The predicted protein-protein interaction networks and canonical pathways were generated using inputs of gene identifiers, log2 fold-changes and p-values between control and treated group comparisons.