All experiments were performed using ICR and C57BL/6J mice purchased from Clea Japan, Inc. Animals were housed in an environment with 12 h dark-light cycle with light on at 7:00 a.m. and provided food (CE-2; Clea Japan, Inc.) and tap water ad libitum. Animals were allowed to acclimatize appropriately to the room before starting experiments. All experiments were reviewed and approved by the Laboratory Animals Ethics Committee of Takeda Pharmaceutical Company Limited.
Icr and c57bl 6j mice
Manufactured by CLEA Japan
Sourced in Japan
The ICR and C57BL/6J mice are laboratory rodents commonly used in research. The ICR mouse is an outbred strain, while the C57BL/6J is an inbred strain. These mice are widely used in various fields of biomedical research, including genetics, immunology, and drug development. The core function of these mice is to serve as model organisms for scientific investigation.
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Lab products found in correlation
2 protocols using icr and c57bl 6j mice
1
Mouse Housing and Acclimatization Protocol
2
Genetic Murine Models for Steroid 5α-Reductase
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All procedures and protocols were approved by the Committee on Animal Research at Wakayama Medical University. Srd5a1 KO mice, Srd5a2 KO mice, and
Flk1-GFP BAC Tg mice were utilized in this study [17 (link),18 (link),19 (link)]. Srd5a1 and Srd5a2 double knockout (Srd5a1/2 DKO) mice were prepared by crossing males and females, which were heterozygous
for type 1 and homozygous for the type 2 [18 (link)]. ICR and C57BL/6J mice were utilized as controls (CLEA Japan, Inc., Tokyo, Japan). Embryonic day 0.5 was
defined as noon on the day when a vaginal plug was detected.
Flk1-GFP BAC Tg mice were utilized in this study [17 (link),18 (link),19 (link)]. Srd5a1 and Srd5a2 double knockout (Srd5a1/2 DKO) mice were prepared by crossing males and females, which were heterozygous
for type 1 and homozygous for the type 2 [18 (link)]. ICR and C57BL/6J mice were utilized as controls (CLEA Japan, Inc., Tokyo, Japan). Embryonic day 0.5 was
defined as noon on the day when a vaginal plug was detected.
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