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Propranolol prop

Manufactured by Merck Group
Sourced in Canada

Propranolol (Prop) is a beta-blocker drug used in the treatment of various cardiovascular conditions. It functions by blocking the effects of the hormone epinephrine, which can help to lower heart rate and blood pressure. Prop is commonly used in the management of hypertension, angina, and certain types of arrhythmias.

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2 protocols using propranolol prop

1

Antibody and Inhibitor Sources for ER Stress

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Rabbit polyclonal anti-hERG was purchased from Alomone (Alomone, Israel). Anti-CNX antibody was purchased from Santa Cruz Biotechnology (Santa Cruz, CA). Anti-CRT antibody was purchased from Abcam (Abcam, U.S.A.). Rabbit polyclonal anti-ATF6 was purchased from Active Motif (Active Motif, U.S.A.). The proteasome inhibitor of N-acetyl-l-leucyl-l-leucyl-l-norleucinal (ALLN) was purchased from Calbiochem, Propranolol (Prop) was purchased from Sigma (Sigma, U.S.A.).
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2

Pharmacological Modulation of GLP-2 and Exendin-4 Signaling

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Custom synthesized human [Gly2]GLP-2, henceforth referred to as GLP-2, was from Pepceutical Ltd. (Nottingham, UK) and recombinant exendin-4 (#7-02177) from CHI Scientific (Maynard, MA). Vasoactive intestinal peptide (VIP, #H-3775), the VIP receptor antagonist [Lys1-Pro2,5-Arg3,4-Tyr6] VIP (VIP-hybrid, #H-9935) [11] (link) and cholecystokinin octapeptide sulfated (CCK8, #H-2080) were purchased from Bachem (Torrance, CA). The NO synthase inhibitor NG-Nitro-l-Arginine Methyl Ester (l-NAME, #N5751), the non-selective beta-adrenergic receptor blocker propranolol (Prop, #P0884), the nicotinic receptor antagonist hexamethonium bromide (HexBr, #H0879), lithocholic acid (LCA, #L6250), and sodium taurocholate (TCA, T4009) were from Sigma Aldrich (Oakville ON, Canada). Tetrodotoxin citrate (TTX, #1069) was from Tocris Biosciences (Minneapolis, MN). Peptides and drugs were dissolved in PBS, except lithocholic acid that was dissolved in dimethyl sulfoxide DMSO, and administered to mice by intraperitoneal injection.
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