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Anti lkb1 antibody

Manufactured by Cell Signaling Technology
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The Anti-LKB1 antibody is a research-use only product that detects the LKB1 protein. LKB1 is a serine/threonine kinase that plays a key role in the regulation of cellular energy metabolism and acts as a tumor suppressor. This antibody can be used for applications such as western blotting to identify and quantify LKB1 expression levels.

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Anti snail, by Thermo Fisher Scientific (1 mentions)

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Anti-LKB1 (18 citations)

2 protocols using anti lkb1 antibody

1

Protein Expression Analysis via Western Blot

Cited 1 time
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Western Blots were performed, as previously described(19 (link)). Anti-LKB1 antibody was purchased from Cell Signaling Technology (Clone 27D10). Anti-GAPDH antibody was from Advanced Immunochemical Inc (Clone 6C5).
Li R., Salehi-Rad R., Crosson W., Momcilovic M., Lim R.J., Ong S.L., Huang Z.L., Zhang T., Abascal J., Dumitras C., Jing Z., Park S.J., Krysan K., Shackelford D.B., Tran L.M., Liu B, & Dubinett S.M. (2021). Inhibition of Granulocytic Myeloid-Derived Suppressor Cells Overcomes Resistance to Immune Checkpoint Inhibition in LKB1-deficient Non-Small Cell Lung Cancer. Cancer research, 81(12), 3295-3308.
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2

Immunohistochemical Analysis of LKB1 and Snail Expression

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The immunological histological chemistry (IHC) analysis was performed as described previously.11 The IHC evaluation of protein expression intensity in PC tissues and normal adjacent tissues was performed independently by 2 pathologists from the department of Pathology, Zhongshan Hospital (Fudan University). The staining intensity was scored as described previously.12The following primary antibodies were used: anti‐LKB1 antibody from Cell Signaling Technology and anti‐Snail from Thermo Fisher.
Song L., Guo J., Chang R., Peng X., Li J., Xu X., Zhan X, & Zhan L. (2018). LKB1 obliterates Snail stability and inhibits pancreatic cancer metastasis in response to metformin treatment. Cancer Science, 109(5), 1382-1392.
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