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Infinium methylationepic 850k platform

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The Infinium MethylationEPIC (850K) platform is a laboratory equipment product developed by Illumina. It is a high-throughput microarray-based technology designed for DNA methylation profiling. The core function of the Infinium MethylationEPIC (850K) platform is to enable comprehensive genome-wide analysis of DNA methylation patterns across more than 850,000 CpG sites.

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Lab products found in correlation

450k methylation array, by Illumina (2 mentions) Infinium humanmethylation450 450k beadchip, by Illumina (2 mentions)

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Infinium platform (29 citations) Infinium MethylationEPIC platform (5 citations) MethylationEPIC (850k) platform (2 citations)

2 protocols using infinium methylationepic 850k platform

1

DNA Methylation Profiling of ATRT and MRT

Cited 2 times
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DNA methylation array data from 150 primary ATRT samples were previously published (Johann et al., 2016 (link)). DNA methylation array data from 9 MRT samples from RBTC were generated using Illumina’s Infinium HumanMethylation450 BeadChip (450K) platform. Using Illumina’s Infinium MethylationEPIC (850K) platform, we generated DNA methylation data for 40 primary MRT samples that previously had been analyzed using whole-genome bisulfite sequencing (Chun et al., 2016 (link)), and also for an additional 11 ATRT and 91 MRT cases. All samples were checked for expected and unexpected genotype matches by pairwise correlation of the 65 genotyping probes on the Illumina Methylation 450K array. Raw 450K/850K data files were generated and processed as previously described (Capper et al., 2018 (link)).
Chun H.J., Johann P.D., Milne K., Zapatka M., Buellesbach A., Ishaque N., Iskar M., Erkek S., Wei L., Tessier-Cloutier B., Lever J., Titmuss E., Topham J.T., Bowlby R., Chuah E., Mungall K.L., Ma Y., Mungall A.J., Moore R.A., Taylor M.D., Gerhard D.S., Jones S.J., Korshunov A., Gessler M., Kerl K., Hasselblatt M., Frühwald M.C., Perlman E.J., Nelson B.H., Pfister S.M., Marra M.A, & Kool M. (2019). Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration. Cell reports, 29(8), 2338-2354.e7.
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2

DNA Methylation Profiling of ATRT and MRT

Cited 2 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
DNA methylation array data from 150 primary ATRT samples were previously published (Johann et al., 2016 (link)). DNA methylation array data from 9 MRT samples from RBTC were generated using Illumina’s Infinium HumanMethylation450 BeadChip (450K) platform. Using Illumina’s Infinium MethylationEPIC (850K) platform, we generated DNA methylation data for 40 primary MRT samples that previously had been analyzed using whole-genome bisulfite sequencing (Chun et al., 2016 (link)), and also for an additional 11 ATRT and 91 MRT cases. All samples were checked for expected and unexpected genotype matches by pairwise correlation of the 65 genotyping probes on the Illumina Methylation 450K array. Raw 450K/850K data files were generated and processed as previously described (Capper et al., 2018 (link)).
Chun H.J., Johann P.D., Milne K., Zapatka M., Buellesbach A., Ishaque N., Iskar M., Erkek S., Wei L., Tessier-Cloutier B., Lever J., Titmuss E., Topham J.T., Bowlby R., Chuah E., Mungall K.L., Ma Y., Mungall A.J., Moore R.A., Taylor M.D., Gerhard D.S., Jones S.J., Korshunov A., Gessler M., Kerl K., Hasselblatt M., Frühwald M.C., Perlman E.J., Nelson B.H., Pfister S.M., Marra M.A, & Kool M. (2019). Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration. Cell reports, 29(8), 2338-2354.e7.
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